NDLI: Gut colonization by Candida albicans aggravates inflammation in the gut and extra-gut tissues in mice.

Please wait, while we are loading the content...

Phylogenetic analysis of Pythium insidiosum Thai strains using cytochrome oxidase II (COX II) DNA coding sequences and internal transcribed spacer regions (ITS).

Probing the role of point mutations in the cyp51A gene from Aspergillus fumigatus in the model yeast Saccharomyces cerevisiae.

Seasonal variations in the prevalence of Cryptococcus neoformans var. grubii and Cryptococcus gattii in decayed wood inside trunk hollows of diverse tree species in north-western India: a retrospective study.

A rare complication of ear piercing: a case of subcutaneous phaeohyphomycosis caused by Veronaea botryosa in China.

Microsporum audouinii tinea capitis in a Swiss school: assessment and management of patients and asymptomatic carriers.

Degradation of fungal DNA in formalin-fixed paraffin-embedded sinus fungal balls hampers reliable sequence-based identification of fungi.

Fatal invasive trichosporonosis due to Trichosporon loubieri in a patient with T-lymphoblastic lymphoma.

Nasal rhinosporidiosis in humans: new interpretations and a review of the literature of this enigmatic disease.

Chronic ulcerative dermatitis caused by Fusarium sporotrichioides.

In vitro interactions among echinocandins against Aspergillus fumigatus: lack of concordance among methods

Biofilm production and evaluation of antifungal susceptibility amongst clinical Candida spp. isolates, including strains of the Candida parapsilosis complex.

Mycoses of implantation in Latin America: an overview of epidemiology, clinical manifestations, diagnosis and treatment.

Changing pattern of Candida species in a neonatal intensive care unit.

Voriconazole: may be an option for treatment of cryptococcal meningitis.

Year: 2011 Volume: 49 Issue: 2

Year: 2011 Volume: 49 Issue: 1

Year: 2011 Volume: 49 Issue: Supplementary 1

Year: 2010 Volume: 48

Year: 2009 Volume: 47

Year: 2008 Volume: 46

Year: 2007 Volume: 45

Year: 2006 Volume: 44

Gut colonization by Candida albicans aggravates inflammation in the gut and extra-gut tissues in mice.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Sonoyama, Kei Miki, Atsuko Sugita, Ryusuke Goto, Haruka Nakata, Mayumi Yamaguchi, Natsu
Description	Country affiliation: Japan Author Affiliation: Sonoyama K ( Research Faculty of Agriculture, Hokkaido University, Sapporo, Hokkaido, Japan. ksnym@chem.agr.hokudai.ac.jp)
Abstract	We examined whether Candida albicans gut colonization aggravates immune diseases in mice. Chronic and latent C. albicans gut colonization was established by the intragastric inoculation of C. albicans in mice fed as part of a purified diet. Allergic diarrhea was induced by repetitive intragastric administration of ovalbumin in sensitized BALB/c mice. Contact hypersensitivity was evaluated by measuring ear swelling after topical application of 2, 4-dinitrofluorobenzene in NC/Nga mice. Arthritis was induced by intradermal injection of bovine type-II collagen emulsified with complete Freund's adjuvant in DBA/1J mice. C. albicans gut colonization increased the incidence of allergic diarrhea, which was accompanied by gut hyperpermeability, as well as increased infiltration of inflammatory cells in the colon. Contact hypersensitivity was also exacerbated by C. albicans gut colonization, as demonstrated by increased swelling, myeloperoxidase activity, and proinflammatory cytokines in ear auricles. Furthermore, C. albicans gut colonization promoted limb joint inflammation in collagen-induced arthritis, in an animal model of rheumatoid arthritis. These findings suggest that C. albicans gut colonization in mice aggravates inflammation in allergic and autoimmune diseases, not only in the gut but also in the extra-gut tissues and underscores the necessity of investigating the pathogenic role of C. albicans gut colonization in immune diseases in humans.
File Format	HTM / HTML
ISSN	13693786
e-ISSN	14602709
Journal	Medical Mycology
Issue Number	3
Volume Number	49
Language	English
Publisher	Oxford University Press
Publisher Date	2011-04-01
Publisher Place	Great Britain (UK)
Access Restriction	Open
Subject Keyword	Discipline Microbiology Discipline Veterinary Medicine Candida Albicans Pathogenicity Candidiasis Immunology Pathology Carrier State Gastrointestinal Tract Microbiology Animals Autoimmune Diseases Disease Models, Animal Hypersensitivity Inflammation Mice Mice, Inbred Balb C Mice, Inbred Dba Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Veterinary

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Adherence, colonization and dissemination of Candida dubliniensis and other Candida species.

Murine model of concurrent oral and vaginal Candida albicans colonization to study epithelial host–pathogen interactions

Effects of levofloxacin, moxifloxacin and prulifloxacin on murine gut colonization by Candida albicans.

Genetically-Regulated Filamentation Contributes to Candida albicans Virulence During Corneal Infection

Candida parapsilosis complex induces local inflammatory cytokines in immunocompetent mice.

Study on the comparative activity of echinocandins on murine gut colonization by Candida albicans.

Absence of TLR2 influences survival of neutrophils after infection with Candida albicans.

Evaluation of in vivo pathogenicity of Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis with different enzymatic profiles in a murine model of disseminated candidiasis.

Distinct stages during colonization of the mouse gastrointestinal tract by Candida albicans

Gut colonization by Candida albicans aggravates inflammation in the gut and extra-gut tissues in mice.

Similar Documents

Adherence, colonization and dissemination of Candida dubliniensis and other Candida species.

Murine model of concurrent oral and vaginal Candida albicans colonization to study epithelial host–pathogen interactions

Effects of levofloxacin, moxifloxacin and prulifloxacin on murine gut colonization by Candida albicans.

Genetically-Regulated Filamentation Contributes to Candida albicans Virulence During Corneal Infection

Candida parapsilosis complex induces local inflammatory cytokines in immunocompetent mice.

Study on the comparative activity of echinocandins on murine gut colonization by Candida albicans.

Absence of TLR2 influences survival of neutrophils after infection with Candida albicans.

Evaluation of in vivo pathogenicity of Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis with different enzymatic profiles in a murine model of disseminated candidiasis.

Distinct stages during colonization of the mouse gastrointestinal tract by Candida albicans

Gut colonization by Candida albicans aggravates inflammation in the gut and extra-gut tissues in mice.