NDLI: Biological effects of polycyclic aromatic hydrocarbons (PAH) and their first metabolic products in in vivo exposed Atlantic cod (Gadus morhua).

Please wait, while we are loading the content...

Lipid peroxidation and oxidative stress responses in juvenile salmon exposed to waterborne levels of the organophosphate compounds tris(2-butoxyethyl)- and tris(2-chloroethyl) phosphates.

Behavioral responses of brown shrimp (Crangon crangon) to reduced seawater pH following simulated leakages from sub-sea geological storage of $CO_{2}$

Endocrine effects of real-life mixtures of persistent organic pollutants (POP) in experimental models and wild fish.

Acute toxicity of dispersed crude oil on the cold-water copepod Calanus finmarchicus: Elusive implications of lipid content.

Exposure of first-feeding cod larvae to dispersed crude oil results in similar transcriptional and metabolic responses as food deprivation.

Predicting environmental risk: A road map for the future.

Individual and molecular level effects of produced water contaminants on nauplii and adult females of Calanus finmarchicus.

Parental exposure to natural mixtures of persistent organic pollutants (POP) induced changes in transcription of apoptosis-related genes in offspring zebrafish embryos.

Transcriptional effects of metal-rich acid drainage water from the abandoned Løkken Mine on Atlantic salmon (Salmo salar) smolt.

Biological effects of polycyclic aromatic hydrocarbons (PAH) and their first metabolic products in in vivo exposed Atlantic cod (Gadus morhua).

An evaluation of coral lophelia pertusa mucus as an analytical matrix for environmental monitoring: A preliminary proteomic study.

Effect of dispersed crude oil on the feeding activity, retention efficiency, and filtration rate of differently sized blue mussels (Mytilus edulis).

Year: 2016 Volume: 79 Issue: 16-17

Year: 2015 Volume: 78

Year: 2014 Volume: 77

Year: 2013 Volume: 76

Year: 2012 Volume: 75

Year: 2011 Volume: 74

Year: 2010 Volume: 73

Year: 2009 Volume: 72

Year: 2008 Volume: 71

Year: 2007 Volume: 70

Year: 2006 Volume: 69

Year: 2004 Volume: 67

Year: 2003 Volume: 66

Year: 2001 Volume: 64

Year: 2000 Volume: 60

Biological effects of polycyclic aromatic hydrocarbons (PAH) and their first metabolic products in in vivo exposed Atlantic cod (Gadus morhua).

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Pampanin, Daniela M. Le Goff, Jeremie Skogland, Karianne Marcucci, Cristian R. Øysæd, Kjell Birger Lorentzen, Marianne Jørgensen, Kåre B. Sydnes, Magne O.
Description	Country affiliation: Norway Author Affiliation: Pampanin DM ( a International Research Institute of Stavanger (IRIS) , Environment Department , Randaberg , Norway.); Le Goff J ( b Adn'tox, Centre François Baclesse , Caen , France.); Skogland K ( a International Research Institute of Stavanger (IRIS) , Environment Department , Randaberg , Norway.); Marcucci CR ( a International Research Institute of Stavanger (IRIS) , Environment Department , Randaberg , Norway.); Øysæd KB ( c Faculty of Science and Technology, Department of Mathematics and Natural Science , University of Stavanger , Stavanger , Norway.); Lorentzen M ( a International Research Institute of Stavanger (IRIS) , Environment Department , Randaberg , Norway.); Jørgensen KB ( c Faculty of Science and Technology, Department of Mathematics and Natural Science , University of Stavanger , Stavanger , Norway.); Sydnes MO ( c Faculty of Science and Technology, Department of Mathematics and Natural Science , University of Stavanger , Stavanger , Norway.)
Abstract	The monitoring of the presence of polycyclic aromatic hydrocarbons (PAH) in the aquatic environment is a worldwide activity since some of these compounds are well-established carcinogens and mutagens. Contaminants in this class are in fact regarded as priority hazardous substances for environmental pollution (Water Framework Directive 2000/60/EC). In this study, Atlantic cod (Gadus morhua) was selected to assess in vivo effects of two PAH and their first metabolic products, namely, the corresponding trans-dihydrodiols, using biological markers. Fish were exposed for 1 wk to a single PAH (naphthalene or chrysene) and its synthetic metabolites ((1R,2R)-1,2-dihydronaphthalene-1,2-diol and (1R,2R)-1,2-dihydrochrysene-1,2-diol) by intraperitoneal injection in a continuous seawater flow system. After exposure, PAH metabolism including PAH metabolites in bile and ethoxyresorufin O-deethylase (EROD) activity, oxidative stress glutathione S-transferases (GST) and catalase (CAT) activities, and genotoxicity such as DNA adducts were evaluated, as well as general health conditions including condition index (CI), hepatosomatic index (HSI), and gonadosomatic index (GSI). PAH metabolite values were low and not significantly different when measured with the fixed-wavelength fluorescence screening method, while the gas chromatography-mass spectroscopy (GC-MS) method showed an apparent dose response in fish exposed to naphthalene. DNA adduct levels ≥0.16 × 10(-8) relative adduct level (RAL) were detected. It should be noted that 0.16 × 10(-8) RAL is considered the maximal acceptable background level for this species. The other biomarkers activities of catalase, GST, and EROD did not display a particular compound- or dose-related response. The GSI values were significantly lower in some chrysene- and in both naphthalene- and naphthalene diol-exposed groups compared to control.
File Format	HTM / HTML
ISSN	15287394
Issue Number	13-15
Journal	Journal of Toxicology and Environmental Health, Part A
Volume Number	79
e-ISSN	10872620
Language	English
Publisher	Taylor & Francis
Publisher Date	2016-01-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Environmental Health Discipline Toxicology
Content Type	Text
Resource Type	Article
Subject	Health, Toxicology and Mutagenesis Toxicology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Study of the bile proteome of Atlantic cod (Gadus morhua): Multi-biological markers of exposure to polycyclic aromatic hydrocarbons.

Endocrine modulation in Atlantic cod (Gadus morhua L.) exposed to alkylphenols, polyaromatic hydrocarbons, produced water, and dispersed oil.

Polycyclic aromatic hydrocarbon (PAH) metabolites in Atlantic cod exposed via water or diet to a synthetic produced water.

Relationship between polycyclic aromatic hydrocarbon (PAH) accumulation in semipermeable membrane devices and PAH bile metabolite levels in Atlantic cod (Gadus morhua).

The influence of water temperature on induced liver EROD activity in Atlantic cod (Gadus morhua) exposed to crude oil and oil dispersants.

Gastrointestinal microbial community changes in Atlantic cod (Gadus morhua) exposed to crude oil

Effects of produced water on reproductive parameters in prespawning Atlantic cod (Gadus morhua).

Repeated sampling of Atlantic cod (Gadus morhua) for monitoring of nondestructive parameters during exposure to a synthetic produced water.

Determination of Polycyclic Aromatic Hydrocarbons (PAH) and Their Metabolites in Blood, Feces, and Urine of Rats Orally Exposed to PAH Contaminated Soils

Biological effects of polycyclic aromatic hydrocarbons (PAH) and their first metabolic products in in vivo exposed Atlantic cod (Gadus morhua).

Similar Documents

Study of the bile proteome of Atlantic cod (Gadus morhua): Multi-biological markers of exposure to polycyclic aromatic hydrocarbons.

Endocrine modulation in Atlantic cod (Gadus morhua L.) exposed to alkylphenols, polyaromatic hydrocarbons, produced water, and dispersed oil.

Polycyclic aromatic hydrocarbon (PAH) metabolites in Atlantic cod exposed via water or diet to a synthetic produced water.

Relationship between polycyclic aromatic hydrocarbon (PAH) accumulation in semipermeable membrane devices and PAH bile metabolite levels in Atlantic cod (Gadus morhua).

The influence of water temperature on induced liver EROD activity in Atlantic cod (Gadus morhua) exposed to crude oil and oil dispersants.

Gastrointestinal microbial community changes in Atlantic cod (Gadus morhua) exposed to crude oil

Effects of produced water on reproductive parameters in prespawning Atlantic cod (Gadus morhua).

Repeated sampling of Atlantic cod (Gadus morhua) for monitoring of nondestructive parameters during exposure to a synthetic produced water.

Determination of Polycyclic Aromatic Hydrocarbons (PAH) and Their Metabolites in Blood, Feces, and Urine of Rats Orally Exposed to PAH Contaminated Soils

Biological effects of polycyclic aromatic hydrocarbons (PAH) and their first metabolic products in in vivo exposed Atlantic cod (Gadus morhua).