NDLI: Focal nodular hyperplasia of the liver: diffusion-weighted magnetic resonance imaging characteristics using high b values.

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Focal nodular hyperplasia of the liver: diffusion-weighted magnetic resonance imaging characteristics using high b values.

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Focal nodular hyperplasia of the liver: diffusion-weighted magnetic resonance imaging characteristics using high b values.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Dohan, Anthony Soyer, Philippe Guerrache, Youcef Hoeffel, Christine Gavini, Jean-Philippe Kaci, Rachid Boudiaf, Mourad
Description	Country affiliation: France Author Affiliation: Dohan A ( From the *Department of Abdominal Imaging, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris)
Abstract	OBJECTIVE: To qualitatively and quantitatively assess the presentation of hepatic focal nodular hyperplasia (FNH) at diffusion-weighted magnetic resonance imaging (DWMRI) using multiple high b values. MATERIALS AND METHODS: Twenty-five patients with 27 FNHs had liver DWMRI at 1.5 T using free-breathing acquisition and 3 b values (0, 600, 1000 s/mm). Focal nodular hyperplasias were evaluated qualitatively using visual analysis of diffusion-weighted magnetic resonance (DWMR) images and quantitatively using conventional apparent diffusion coefficient (ADC) and normalized ADC measurements. RESULTS: All FNHs (100%) were visible on b0 DWMR images; 26 of the 27 FNHs (96%), on b600 DWMR images; and 21 of the 27 FNHs (78%), on b1000 DWMR images. A total of 18 of the 27 FNHs (67%) exhibited a hyperintense central scar on the b0 DWMR images that remained visible on the b600 and b1000 DWMR images in 6 of the 27 FNHs (22%). Conventional ADC value of FNHs (1.318 × 10 mm/±0.208) was significantly lower than that of adjacent hepatic parenchyma (1.414 × 10 mm/s ± 1.95) (P = 0.0003), although a substantial overlap was found. The use of normalized ADC using the liver as reference organ resulted in a more restricted distribution of ADC values (variation coefficient, 5.3%). CONCLUSIONS: Focal nodular hyperplasias show a wide range of morphological features at DWMRI using high b values. Further studies are needed to fully investigate as to what extent normalized ADC may result in better lesion characterization.
File Format	HTM / HTML
ISSN	03638715
Issue Number	1
Volume Number	38
e-ISSN	15323145
Journal	Journal of Computer Assisted Tomography
Language	English
Publisher	Lippincott Williams & Wilkins
Publisher Date	2014-01-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Radiology Diffusion Magnetic Resonance Imaging Methods Focal Nodular Hyperplasia Diagnosis Adult Aged Algorithms Contrast Media Female Pathology Humans Male Meglumine Middle Aged Organometallic Compounds Retrospective Studies Tomography, Spiral Computed Ultrasonography, Doppler Journal Article
Content Type	Text
Resource Type	Article
Subject	Radiology, Nuclear Medicine and Imaging

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