NDLI: Heat acclimation of an adult female with a large surface area of grafted skin.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Wingo, Jonathan E. Low, David A. Keller, David M. Davis, Scott L. Kowalske, Karen J. Purdue, Gary F. Hunt, John L. Crandall, Craig G.
Description	Country affiliation: United States Author Affiliation: Wingo JE ( Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, Texas 75231, USA.)
Abstract	Grafted skin has impaired blood flow and sweating responses necessary for heat dissipation. Heat acclimation improves temperature regulation in healthy individuals, but it is unknown whether heat acclimation improves temperature regulation of individuals with large areas of grafted skin. A 33-year-old woman with 75% total body surface area grafted skin 14 years postinjury performed upright cycling exercise at 45% peak oxygen uptake (50 W) for seven consecutive days in a climatic chamber set to 40 degrees C and 30% relative humidity. The daily goal was for this patient to exercise 90 minutes (with a 5-minute break at minute 45); however, exercise was stopped when an internal temperature (Tc) limit of 39.5 degrees C was reached. The Tc limit was reached during minute 46 of exercise on day 1 of acclimation, but not until minute 65 of exercise on day 7 of acclimation. The increases in Tc and heart rate during the first 45 minutes of exercise (the minimum duration completed for all acclimation bouts) were progressively mitigated with successive days of heat acclimation. Sweat sensitivity (the increase in sweat rate per 1 degrees C increase in Tc) in an area of uninjured skin increased by approximately 30% on acclimation day 7 relative to day 1. Heat acclimation improved thermal tolerance of this patient with a large area of grafted skin, which could increase safety and comfort during thermal stress and/or exercise.
File Format	HTM / HTML
ISSN	1559047X
e-ISSN	15590488
DOI	10.1097/BCR.0b013e3181848b5d
Journal	Journal of Burn Care & Research
Issue Number	5
Volume Number	29
Language	English
Publisher	Lippincott Williams & Wilkins
Publisher Date	2008-09-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Discipline Traumatology Acclimatization Body Surface Area Body Temperature Regulation Body Temperature Burns Etiology Hot Temperature Adverse Effects Skin Transplantation Adaptation, Physiological Surgery Stress, Physiological Time Factors Research Support, N.i.h., Extramural
Content Type	Text
Resource Type	Article
Subject	Emergency Medicine Rehabilitation Surgery

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