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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Beaudreuil, Johann Lermusiaux, Jean-Luc Teyssedou, Jean-Pierre Lahalle, Sophie Lasbleiz, Sandra Bernabé, Brigitte Lellouche, Henri Orcel, Philippe Bardin, Thomas |
| Description | Country affiliation: France Author Affiliation: Beaudreuil J ( Unité rhumatologique des affections de la main, service de rhumatologie, Université Paris-7, Paris, France. johann.beaudreuil@lrb.aphp.fr) |
| Abstract | AIM: To assess the safety and efficacy of multi-needle aponeurotomy (MNA) for advanced Duputren's disease. METHODS: This prospective study included patients with age more than 17 years, Dupuytren's contracture with palmo-digital or poly-digital involvement, presumed NA number needed to treat>4, and availability for at least 1-month follow-up after MNA. Outcome measures were Tubiana score and passive extension deficit, after MNA and at 1 and 6 months; self-assessed disability and satisfaction at 1 and 6 months; and adverse events (AEs). RESULTS: Thirty patients were included. MNA was performed on 37 hands and 99 rays. Among 25 assessed MNA sessions for treatment-related discomfort, patients considered 22 (88%) not at all to moderately painful. Six minor AEs, representing 2 for every 100 NAs, were reported. Tubiana scores at baseline (5.3±2.3, n=35) were improved after treatment (1.7±1.8, n=32, P<0.0001), at 1 month (2.2±1.4, n=26, P<0.0001) and at 6 months (2.8±2.7, n=19, P<0.01). Passive extension deficit was greatly reduced after treatment and persisted at follow-up. Disability scores at baseline (27.6±26.9, n=37) were reduced at 1 month (13.2±19.5, n=26, P=0.02) and at 6 months (5.2±11.6, n=20, P<0.001). Patients were highly satisfied at 1 month (100%, n=25) and 6 months (95%, n=19). CONCLUSION: MNA appears safe and effective for advanced Dupuytren's disease. It could become a treatment of reference and contribute to reducing the need for surgery in this indication. |
| File Format | HTM / HTML |
| ISSN | 1297319X |
| Issue Number | 6 |
| Volume Number | 78 |
| e-ISSN | 17787254 |
| Journal | Joint Bone Spine |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2011-12-01 |
| Publisher Place | France |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Rheumatology Dupuytren Contracture Therapy Fascia Physiopathology Needles Orthopedic Procedures Instrumentation Methods Aged Disability Evaluation Female Follow-up Studies Humans Male Middle Aged Adverse Effects Outcome Assessment (health Care) Patient Satisfaction Prospective Studies Retrospective Studies Self Report Severity Of Illness Index Treatment Outcome Clinical Trial Journal Article |
| Content Type | Text |
| Resource Type | Article |
| Subject | Rheumatology |
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