NDLI: Immunoassay-based screening of polychlorinated biphenyls (PCB) in sediments: requirements for a new generation of test kits.

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Immunoassay-based screening of polychlorinated biphenyls (PCB) in sediments: requirements for a new generation of test kits.

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Immunoassay-based screening of polychlorinated biphenyls (PCB) in sediments: requirements for a new generation of test kits.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Castro-Jiménez, Javier Gonzalez, Catherine
Description	Country affiliation: France Author Affiliation: Castro-Jiménez J ( Environnement Industriel et Risques Industriels et Naturels (LGEI), Ecole des Mines d'Alés, 6 Avenue de Clavières, 30319 Ales cedex, France. javier.castro-jimenez@idaea.csic.es)
Abstract	Polychlorinated biphenyls (PCBs) have been proposed for the inclusion in the European Water Framework Directive (WFD) priority list, currently under revision. Various screening methods have been employed for PCB determination in different environmental matrixes in the last decades, immunoassays being one of the most employed. A literature review reveals that the enzyme-linked immunosorbent assay (ELISA) is the most commonly applied immunoassay for PCB determination in the environment. However, its application to sediments is very limited. A suitability assessment of immunoassay-based analysis for PCB screening in sediments is presented in this work. The significance of available immunoassay-based test kits under the current environmental pollution scenario and their performance against the sensitivity and specificity requirements dictated by the WFD for PCB analysis in sediments is discussed. For example, current detection limits of available test kits for PCB determination in sediments may not be enough for compliance checking under the WFD. In addition, concentration expressed as Aroclor equivalents does not seem to be the way forward. A proposal for adapting available test kits in order to become more suitable tools for PCB screening in sediments is also presented in this study.
File Format	HTM / HTML
ISSN	14640325
Issue Number	4
Volume Number	13
e-ISSN	14640333
Journal	Journal of Environmental Monitoring
Language	English
Publisher	Royal Society of Chemistry
Publisher Date	2011-04-01
Publisher Place	Great Britain (UK)
Access Restriction	Subscribed
Subject Keyword	Discipline Environmental Health Enzyme-linked Immunosorbent Assay Methods Geologic Sediments Chemistry Polychlorinated Biphenyls Analysis Water Pollutants, Chemical Animals Limit Of Detection Journal Article Review
Content Type	Text
Resource Type	Article
Subject	Public Health, Environmental and Occupational Health Management, Monitoring, Policy and Law

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