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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Ahtiainen, J. P. Hulmi, J. J. Kraemer, W. J. Lehti, M. Pakarinen, A. Mero, A. A. Karavirta, L. Sillanpää, E. Selänne, H. Alen, M. Komulainen, J. Kovanen, V. Nyman, K. Häkkinen, K. |
| Description | Country affiliation: Finland Author Affiliation: Ahtiainen JP ( Department of Biology of Physical Activity, University of Jyväskylä, Jyväskylä, Finland. juha.ahtiainen@jyu.fi) |
| Abstract | We investigated whether the myosin heavy chain (MyHC) proportion and androgen receptor (AR) concentration in skeletal muscle differ following 21 weeks of strength, endurance and combined training in untrained older men. Strength (S) and endurance (E) groups trained twice per week and combined (S+E) group trained four times per week (two strength and two endurance). Muscle biopsies were obtained before and after the training period from m. vastus lateralis (VL) and AR mRNA and protein concentration and MyHC proportion were determined. 1RM increased during the training period in S, S+E and E but the changes were greater in S and S+E than in E. Statistically significant increases were observed only in S and S+E in maximal isometric force as well as in VL thickness. VO (2max) increased significantly only in E. MyHCIIa proportion increased in S, while MyHCIIa proportion decreased and MyHCI increased (p<0.05) in E. No statistically significant changes were observed in serum testosterone and in AR mRNA or protein concentrations. The present results indicate that 21 weeks of strength, endurance or combined training changed MyHC proportion according to the training method but did not have an effect on AR mRNA or protein expression in skeletal muscle at rest. |
| File Format | HTM / HTML |
| ISSN | 01724622 |
| Issue Number | 12 |
| Volume Number | 30 |
| e-ISSN | 14393964 |
| Journal | International Journal of Sports Medicine |
| Language | English |
| Publisher | Thieme |
| Publisher Date | 2009-12-01 |
| Publisher Place | Germany |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Sports Medicine Myosin Heavy Chains Metabolism Receptors, Androgen Resistance Training Methods Aged Exercise Physiology Humans Isometric Contraction Male Middle Aged Muscle, Skeletal Oxygen Consumption Physical Endurance Quadriceps Muscle Rna, Messenger Testosterone Blood Comparative Study Journal Article Randomized Controlled Trial |
| Content Type | Text |
| Resource Type | Article |
| Subject | Orthopedics and Sports Medicine Physical Therapy, Sports Therapy and Rehabilitation Sports Science |
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