NDLI: Genetic analysis of 15 autosomal and 12 Y-STR loci in the Espirito Santo State population, Brazil.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Wolfgramm, Eldamária de Vargas Silva, Beatriz Candida Aguiar, Vitor Resende da Costa Malta, Frederico Scott Varela de Castro, Amanda Mafia Ferreira, Alessandro Clayton de Souza Prezoti, Alessandra Nunes Loureiro de Paula, Flavia Louro, Iúri Drumond
Spatial Coverage	Brazil
Description	Country affiliation: Brazil Author Affiliation: Wolfgramm Ede V ( Núcleo de Genética Humana e Molecular, Departamento de Ciências Biológicas, Centro de Ciências Humanas e Naturais, Universidade Federal do Espírito Santo, Av. Marechal Campos, 1468 Campus de Maruípe, CEP 29040-090 Vitória, ES, Brazil.)
Abstract	This study provides population genetic data for individuals of Vitoria, Espirito Santo, Brazil, a location not yet characterized for STR frequencies used for genetic identification studies. Allelic frequencies and other population data analysis are reported for the 15 autosomal-STR loci included in the PowerPlex(®)16 kit (CSF1PO, D13S317, D16S539, D18S51, D21S11, D3S1358, D5S818, D7S820, D8S1179, FGA, Penta D, Penta E, TPOX, TH01 and vWA). Allele and haplotype frequencies, gene diversity and discrimination capacity were also estimated for the PowerPlex(®) Y System (DYS19, DYS385, DYS389I/II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438 and DYS439). Blood samples were obtained from 226 unrelated volunteers (135 males and 91 females) residents in the city of Vitoria, representing a typical sample of the mixed ethnicity present in the Espirito Santo State, Brazil. Within the tested population, the total number of individuals typed for specific markers is: 226 for D13S317, D21S11, D3S1358, D7S820, D8S1179 and FGA; 225 for D16S539 and D5S818; 224 for D18S51; 223 for CSF1PO; 222 for Penta D and vWA; 220 for Penta E; 207 for TPOX and 142 for TH01. Y-STR haplotypes were analyzed for 102 unrelated males, being 71 of them present in the 135 autosomal-STR sample, and 31 new males tested only for Y-STR markers. All autosomal markers were in Hardy-Weinberg Equilibrium. Y-STR analysis identified 101 haplotypes, being 100 of them unique.
File Format	HTM / HTML
ISSN	18724973
Issue Number	3
Volume Number	5
e-ISSN	18780326
Journal	Forensic Science International: Genetics
Language	English
Publisher	Elsevier
Publisher Date	2011-06-01
Publisher Place	Netherlands
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Forensic Sciences Genetic Markers Genetics, Population Microsatellite Repeats Genetics Brazil Gene Frequency Haplotypes Humans Male Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Genetics Pathology and Forensic Medicine

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