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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Park, Jae-Woo Yoon, Jeungwon Cho, Chong-Kwan Lee, Yeon-Weol Yoo, Hwa-Seung |
| Description | Author Affiliation: Park JW ( East-West Cancer Center, Dunsan Oriental Hospital of Daejeon University, 1136 Dunsandong Seogu Daejeon, 302-122, Soul, Korea.) |
| Abstract | OBJECTIVE: To evaluate the efficacy of HangAm-Plus (HAP) on stage IV metastatic gastric cancer by analyzing the treated patients' overall survival outcome. METHODS: Following the study eligibility, overall survival and one year survival rate of 44 stage IV metastatic gastric cancer patients who visited East-West Cancer Center (EWCC) were analyzed. The study consisted of two arms: HAP treatment only (n=18) and combined treatment of concurrent conventional chemotherapy and HAP (n=26). Patient characteristics by gender, age, surgical intervention, Eastern Cooperative Oncology Group (ECOG) score, treatment duration (< 4 weeks or [Symbol: see text]4 weeks), and lines of the chemotherapy received were assessed. Treatment related side effects were also assessed. RESULTS: The median survival of combined group was longer (10.0 months) than that of HAP group (5.1 months). One-year survival rate of combined treatment group and HAP group was 38.5%±9.5% and 33.3%±11.1%, respectively (P>0.05). One-year survival rate of those received more and less than 4-week treatment was 57.1%±18.7% and 8.3%±8.0%, respectively (P=0.001). CONCLUSIONS: The study supports the safety and potential efficacy of HAP treatment in prevention of chemo-related side effects for stage IV metastatic gastric cancer treated with conventional chemotherapy. Further studies are needed to investigate and confirm the results before applying the treatment in clinical settings. |
| File Format | HTM / HTML |
| ISSN | 16720415 |
| Issue Number | 1 |
| Volume Number | 20 |
| e-ISSN | 19930402 |
| Journal | Chinese Journal of Integrative Medicine |
| Language | English |
| Publisher | Springer |
| Publisher Date | 2014-01-01 |
| Publisher Place | China |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Therapeutics Drugs, Chinese Herbal Therapeutic Use Stomach Neoplasms Drug Therapy Pathology Adult Aged Aged, 80 And Over Adverse Effects Female Humans Male Middle Aged Neoplasm Metastasis Neoplasm Staging Survival Analysis Young Adult Clinical Trial Journal Article |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pharmacology (medical) Complementary and Alternative Medicine |
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