NDLI: Use of the novel thrombopoietin receptor-agonist romiplostim, in combination with steroids and immunoglobulins for the increase of platelets prior to splenectomy, in refractory immune thrombocytopenia: a case report.

Please wait, while we are loading the content...

Year: 2017 Volume: 28

Year: 2016 Volume: 27

Year: 2015 Volume: 26

Year: 2014 Volume: 25

Year: 2013 Volume: 24

Year: 2012 Volume: 23

Year: 2012 Volume: 23 Issue: 8

Year: 2012 Volume: 23 Issue: 6

Year: 2012 Volume: 23 Issue: 5

Year: 2012 Volume: 23 Issue: 4

Use of objective efficacy criteria for evaluation of von Willebrand factor/factor VIII concentrates.

Evidence for direct transfer of tissue factor from monocytes to platelets in whole blood.

Use of the novel thrombopoietin receptor-agonist romiplostim, in combination with steroids and immunoglobulins for the increase of platelets prior to splenectomy, in refractory immune thrombocytopenia: a case report.

Novel mutation in the glycoprotein Ibß in a patient with Bernard-Soulier syndrome: possibility of distant parental consanguinity.

Procoagulant activity in patients with sickle cell trait.

Epidemiology of primary and secondary thrombocytopenia: first analysis of an administrative database in a major Italian institution.

Comparative efficacy of different doses of fibrin sealant to reduce bleeding after total knee arthroplasty.

Hypothermic anticoagulation: testing individual responses to graded severe hypothermia with thromboelastography.

Biochemical, mechanical, and morphological properties of a completely autologous platelet-rich wound sealant.

Discard first tube for coagulation testing.

The condensed MCMDM-1 VWD bleeding questionnaire as a predictor of bleeding disorders in women with unexplained menorrhagia.

Laboratory diagnostic approach of the parents-children relationship in differentiating low-level von Willebrand factor from mild type 1 von Willebrand disease.

Cause of deep venous thrombosis and pulmonary embolism in young patients from India as compared with other ethnic groups.

Rituximab as prophylaxis in chronic relapsing thrombotic thrombocytopenic purpura: a case report and review of the literature.

Year: 2012 Volume: 23 Issue: 3

Year: 2012 Volume: 23 Issue: 2

Year: 2012 Volume: 23 Issue: 1

Year: 2011 Volume: 22

Year: 2010 Volume: 21

Year: 2009 Volume: 20

Year: 2008 Volume: 19

Use of the novel thrombopoietin receptor-agonist romiplostim, in combination with steroids and immunoglobulins for the increase of platelets prior to splenectomy, in refractory immune thrombocytopenia: a case report.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Sivera, Piera Ruella, Marco Gueli, Angela Hu, Huijing Wade, Muhamed Tarella, Corrado
Description	Country affiliation: Italy Author Affiliation: Sivera P ( S.C.D.U. Ematologia e Terapie Cellulari, A.O. Ord. Mauriziano-Umberto I, Torino, Italy.)
Abstract	This case report describes a patient with relapsed primary immune thrombocytopenic purpura (ITP), in which splenectomy was not possible due to the persistence of a low platelet count despite treatment with corticosteroids, intravenous immunoglobulins (IVIG) and platelet transfusion treatment. As an attempt to increase platelet count prior to performing splenectomy, the thrombopoietin receptor agonist, romiplostim, was administered in combination with steroids and IVIG. A single administration of romiplostim was found to be markedly effective, allowing a rapid and notable platelet increase, required for a well tolerated splenectomy. This case confirms the potent activity of romiplostim in ITP, and indicates that patients with recurrent primary ITP who are unresponsive to conventional immunosuppressive therapy may benefit from the addition of a short course of romiplostim.
File Format	HTM / HTML
ISSN	09575235
Issue Number	4
Volume Number	23
e-ISSN	14735733
Journal	Blood Coagulation & Fibrinolysis
Language	English
Publisher	Lippincott Williams & Wilkins
Publisher Date	2012-06-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Hematology Blood Platelets Drug Effects Immunoglobulins Therapeutic Use Purpura, Thrombocytopenic, Idiopathic Drug Therapy Receptors, Fc Receptors, Thrombopoietin Agonists Recombinant Fusion Proteins Steroids Thrombopoietin Adult Female Humans Platelet Count Blood Surgery Splenectomy Methods Case Reports Journal Article
Content Type	Text
Resource Type	Case study Article
Subject	Hematology

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in