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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Talebi, Tony N. Manoharan, Murugesan Singal, Rakesh |
| Description | Country affiliation: United States Author Affiliation: Talebi TN ( Division of Hematology/Oncology, University of Miami Sylvester Comprehensive Cancer Center, Miami, FL 33136, USA. tony0272@gmail.com) |
| Abstract | Patients with metastatic hormone-refractory prostate carcinoma may have dramatic and life-threatening coagulation complications from their disease. They are at risk for either clotting or bleeding events. We report the case of a man with metastatic castration-resistant prostate cancer with disseminated intravascular coagulation who had both clotting and bleeding in addition to thrombocytopenia. The patient did not respond to supportive therapy and was treated with docetaxel despite a platelet count of 46/mm³. The treatment resulted in resolution of disseminated intravascular coagulation, normalization of the platelet count, and resolution of hematuria. We review disseminated intravascular coagulation in prostate cancer and different possible treatments. |
| File Format | HTM / HTML |
| ISSN | 10752765 |
| Issue Number | 1 |
| Volume Number | 19 |
| e-ISSN | 15363686 |
| Journal | American Journal of Therapeutics |
| Language | English |
| Publisher | Lippincott Williams & Wilkins |
| Publisher Date | 2012-01-01 |
| Publisher Place | United States |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Pharmacology Disseminated Intravascular Coagulation Drug Therapy Prostatic Neoplasms Taxoids Therapeutic Use Thrombocytopenia Aged, 80 And Over Antineoplastic Agents Etiology Hematuria Humans Male Platelet Count Complications Pathology Treatment Outcome Case Reports Journal Article |
| Content Type | Text |
| Resource Type | Case study Article |
| Subject | Pharmacology Pharmacology (medical) |
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