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Target detection: magnetic resonance imaging-ultrasound fusion-guided prostate biopsy.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Sonn, Geoffrey A. Margolis, Daniel J. Marks, Leonard S.
Description	Country affiliation: Canada Author Affiliation: Sonn GA ( Department of Urology, Stanford University, Stanford, CA.); Margolis DJ ( Department of Radiology, University of California, Los Angeles, CA.); Marks LS ( Department of Urology, University of California, Los Angeles, CA. Electronic address: lmarks@mednet.ucla.edu.)
Abstract	Recent advances in multiparametric magnetic resonance imaging (MRI) have enabled image-guided detection of prostate cancer. Fusion of MRI with real-time ultrasound (US) allows the information from MRI to be used to direct biopsy needles under US guidance in an office-based procedure. Fusion can be performed either cognitively or electronically, using a fusion device. Fusion devices allow superimposition (coregistration) of stored MRI images on real-time US images; areas of suspicion found on MRI can then serve as targets during US-guided biopsy. Currently available fusion devices use a variety of technologies to perform coregistration: robotic tracking via a mechanical arm with built-in encoders (Artemis/Eigen, BioJet/Geoscan); electromagnetic tracking (UroNav/Philips-Invivo, Hi-RVS/Hitachi); or tracking with a 3D US probe (Urostation/Koelis). Targeted fusion biopsy has been shown to identify more clinically significant cancers and fewer insignificant cancers than conventional biopsy. Fusion biopsy appears to be a major advancement over conventional biopsy because it allows (1) direct targeting of suspicious areas not seen on US and (2) follow-up biopsy of specific cancerous sites in men undergoing active surveillance.
File Format	HTM / HTML
ISSN	10781439
e-ISSN	18732496
DOI	10.1016/j.urolonc.2013.08.006
Journal	Urologic Oncology: Seminars and Original Investigations
Issue Number	6
Volume Number	32
Language	English
Publisher	Elsevier
Publisher Date	2014-08-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Discipline Urology Discipline Oncology Image-guided Biopsy Magnetic Resonance Imaging Prostate Pathology Prostatic Neoplasms Ultrasonography, Interventional Diagnosis Reproducibility Of Results Sensitivity And Specificity
Content Type	Text
Resource Type	Article
Subject	Urology Oncology

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Targeted prostate biopsy using magnetic resonance imaging-ultrasound fusion.

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