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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Thorsby, E. Flåm, S. T. Woldseth, B. Dupuy, B. M. Sanchez-Mazas, A. Fernandez-Vina, M. A. |
| Spatial Coverage | Polynesia |
| Description | Country affiliation: Norway Author Affiliation: Thorsby E ( Institute of Immunology, Rikshospitalet University Hospital and University of Oslo, Oslo, Norway. erik.thorsby@medisin.uio.no) |
| Abstract | Available evidence suggests a Polynesian origin of the Easter Island population. We recently found that some native Easter Islanders also carried some common American Indian (Amerindian) human leukocyte antigen (HLA) alleles, which probably were introduced before Europeans discovered the island in 1722. In this study, we report molecular genetic investigations of 21 other selected native Easter Islanders. Analysis of mitochondrial DNA and Y chromosome markers showed no traces of an Amerindian contribution. However, high-resolution genomic HLA typing showed that two individuals carried some other common Amerindian HLA alleles, different from those found in our previous investigations. The new data support our previous evidence of an Amerindian contribution to the gene pool on Easter Island. |
| File Format | HTM / HTML |
| ISSN | 20592302 |
| Issue Number | 6 |
| Volume Number | 73 |
| e-ISSN | 20592310 |
| Journal | Tissue Antigens |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2009-06-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Genetics Discipline Immunology Gene Pool Hla Antigens Genetics Indians, South American Adult Aged Aged, 80 And Over Gene Frequency Genetics, Population Hla-a Antigens Hla-b Antigens Hla-c Antigens Hla-dq Antigens Hla-dq Alpha-chains Hla-dr Antigens Hla-drb1 Chains Haplotypes Humans Middle Aged Polynesia Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Genetics Immunology and Allergy Immunology |
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