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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Chang, Young Suk Kim, Jae Hui Kim, Jong Woo Lee, Tae Gon Kim, Chul Gu |
| Description | Responsible library: WPRO |
| Abstract | PURPOSE: To evaluate the efficacy of an optical coherence tomography (OCT)-based diagnosis of polypoidal choroidal vasculopathy (PCV) in Korean patients. METHODS: This retrospective, observational case series included 263 eyes of 263 patients (147 eyes with PCV and 116 eyes with typical exudative, age-related macular degeneration [AMD]) who had been diagnosed with treatment na?ve exudative AMD. Eyes with three or more of the following OCT findings were diagnosed with PCV: multiple retinal pigment epithelial detachment (RPED), a sharp RPED peak, an RPED notch, a hyporeflective lumen representing polyps, and hyperreflective intraretinal hard exudates. The OCT-based diagnosis was compared with the gold-standard indocyanine green angiography-based method. The sensitivity and specificity of the OCT-based diagnosis was also estimated. An additional analysis was performed using a choroidal thickness criterion. Eyes with a subfoveal choroidal thickness greater than 300 ?m were also diagnosed with PCV despite having only two OCT features. RESULTS: In eyes with PCV, three or more OCT features were observed in 126 of 147 eyes (85.7%), and the incidence of typical exudative AMD was 16 of 116 eyes (13.8%). The sensitivity and specificity of an OCT-based diagnosis were 85.7% and 86.2%, respectively. After applying the choroidal thickness criterion, the sensitivity increased from 85.7% to 89.8%, and the specificity decreased from 86.2% to 84.5%. CONCLUSIONS: The OCT-based diagnosis of PCV showed a high sensitivity and specificity in Korean patients. The addition of a choroidal thickness criterion improved the sensitivity of the method with a minimal decrease in its specificity. |
| File Format | HTM / HTML |
| ISSN | 10118942 |
| e-ISSN | 20929382 |
| Journal | Korean Journal of Ophthalmology |
| Issue Number | 3 |
| Volume Number | 30 |
| Language | English |
| Publisher | Korean Ophthalmological Society |
| Publisher Date | 2016-01-01 |
| Publisher Place | Korea (South) |
| Access Restriction | Open |
| Subject Keyword | Discipline Ophthalmology Choroid Choroidal Neovascularization Diagnosis Exudates And Transudates Indocyanine Green Macular Degeneration Polyps Retinal Detachment Retrospective Studies Sensitivity And Specificity Tomography, Optical Coherence Original Article |
| Content Type | Text |
| Resource Type | Article |
| Subject | Ophthalmology |
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