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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Pollak, Lea Shlamkovic, Natan Minewicz, Alla Mirovsky, Yigal |
| Description | Country affiliation: Israel Author Affiliation: Pollak L ( Departments of Neurology, The Assaf Harofeh Medical Center, Sackler Faculty of Medicine, University of Tel Aviv, Nes Ziona, Israel. lea.pollak@gmail.com) |
| Abstract | BACKGROUND: To investigate whether otolith system, as a major contributor to muscles for postural control, might play a role in the pathogenesis of idiopathic scoliosis (IS). METHODS: Cervical vestibular-evoked myogenic potentials (VEMP) testing was applied to investigate the otolith function in patients with IS. Twenty-nine healthy patients (mean age 13.5±2.5 y, 4 males) were included. In all but 2 patients, the major curve deviation was to the right and the mean angle deviation was 49.7±21.6 degrees. Nineteen age-matched individuals (10 males) served as controls. RESULTS: The P13 (first positive wave) latencies were comparable in both groups. Patients with IS had significantly longer N23 (first negative wave) latencies than controls. A high correlation between the age and N23 latencies on the right was found in IS patients. A link between the scoliosis angle and VEMP latencies could not be demonstrated.The VEMP amplitudes were higher in patients than in controls, whereas the amplitude asymmetry ratio was similar in both groups. CONCLUSIONS: This work brings further evidence for vestibular abnormalities in patients with IS. Prospective studies are needed to elucidate a possible causative relationship between otolith dysfunction and the development of scoliosis. LEVEL OF EVIDENCE: III. |
| File Format | HTM / HTML |
| ISSN | 02716798 |
| Issue Number | 3 |
| Volume Number | 33 |
| e-ISSN | 15392570 |
| Journal | Journal of Pediatric Orthopaedics |
| Language | English |
| Publisher | Lippincott Williams & Wilkins |
| Publisher Date | 2013-04-01 |
| Publisher Place | United States |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Orthopedics Otolithic Membrane Physiopathology Scoliosis Etiology Vestibular Evoked Myogenic Potentials Adolescent Child Female Humans Male Young Adult Journal Article |
| Content Type | Text |
| Resource Type | Article |
| Subject | Orthopedics and Sports Medicine Pediatrics, Perinatology and Child Health |
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