NDLI: Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology.

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Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Schunck, Michael Zague, Vivian Oesser, Steffen Proksch, Ehrhardt
Description	Country affiliation: Germany Author Affiliation: Schunck M ( 1 CRI, Collagen Research Institute , Kiel, Germany .); Zague V ( 2 Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo , São Paulo, Brazil .); Oesser S ( 1 CRI, Collagen Research Institute , Kiel, Germany .); Proksch E ( 3 Department of Dermatology, Christian-Albrechts-University of Kiel , Kiel, Germany .)
Abstract	In this double-blind, placebo-controlled clinical study, we investigated the efficacy of specific bioactive collagen peptides (BCP) on the cellulite treatment of normal and overweight women. In total, 105 women aged 24-50 years with moderate cellulite were randomized to orally receive a daily dosage of 2.5 g BCP or a placebo over 6 months. The degree of cellulite was evaluated before starting the treatment and after 3 and 6 months of intake. In addition, skin waviness, dermal density, and the length of subcutaneous borderline were assessed. BCP treatment led to a statistically significant decrease in the degree of cellulite and a reduced skin waviness on thighs (P < 0.05) in normal weight women. Moreover, dermal density was significantly improved (P < 0.05) compared to placebo. The subcutaneous borderline showed a significant shortening after BCP intake compared to the beginning of the study, indicating cellulite improvement, but the data failed to reach statistical significance compared to placebo. The efficacy of BCP treatment was also confirmed in overweight women, although the impact was less pronounced in comparison with women of normal body weight. The results of the study demonstrated that a regular ingestion of BCP over a period of 6 months led to a clear improvement of the skin appearance in women suffering from moderate cellulite. Based on the current data, it can be concluded that a long-term therapy with orally administered BCP leads to an improvement of cellulite and has a positive impact on skin health.
File Format	HTM / HTML
ISSN	1096620X
e-ISSN	15577600
DOI	10.1089/jmf.2015.0022
Journal	Journal of Medicinal Food
Issue Number	12
Volume Number	18
Language	English
Publisher	Mary Ann Liebert, Inc.
Publisher Date	2015-12-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Discipline Nutritional Sciences Adipose Tissue Body Mass Index Collagen Pharmacology Dietary Supplements Peptides Skin Thigh Metabolism Double-blind Method Obesity Complications Reference Values Randomized Controlled Trial
Content Type	Text
Resource Type	Article
Subject	Nutrition and Dietetics Medicine

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