NDLI: Morphology, drug release, antibacterial, cell proliferation, and histology studies of chamomile-loaded wound dressing mats based on electrospun nanofibrous poly(É-caprolactone)/polystyrene blends.

Please wait, while we are loading the content...

Segmental mandibular bone reconstruction with a carbonate-substituted hydroxyapatite-coated modular endoprosthetic poly(É-caprolactone) scaffold in Macaca fascicularis.

Morphology, drug release, antibacterial, cell proliferation, and histology studies of chamomile-loaded wound dressing mats based on electrospun nanofibrous poly(É-caprolactone)/polystyrene blends.

Plasma electrolytic oxidation coatings on Î³TiAl alloy for potential biomedical applications.

Biomimetic myocardial patches fabricated with poly(É-caprolactone) and polyethylene glycol-based polyurethanes.

Role of biomaterials in prevention of in-stent restenosis.

Effects of bone marrow-derived mesenchymal stem cells and platelet-rich plasma on bone regeneration for osseointegration of dental implants: preliminary study in canine three-wall intrabony defects.

In vivo testing of silver treated fibers for the evaluation of skin irritation effect and hypoallergenicity.

Enhanced osteoconductivity of sodium-substituted hydroxyapatite by system instability.

Preparation of an autologous heart valve with a stent (stent-biovalve) using the stent eversion method.

Evaluation of biocompatibility and degradation of chitosan nanofiber membrane crosslinked with genipin.

Biocompatibility and tissue integration of a novel shape memory surgical mesh for ventral hernia: in vivo animal studies.

Synthetic niches for differentiation of human embryonic stem cells bypassing embryoid body formation.

Metallic oxide nanoparticles stimulate blood coagulation independent of their surface charge

Preparation and evaluation of PEO-coated materials for a microchannel hemodialyzer.

A protocol for rheological characterization of hydrogels for tissue engineering strategies.

Molded polymer-coated composite bone void filler improves tobramycin controlled release kinetics.

Year: 2014 Volume: 102 Issue: 4

Year: 2014 Volume: 102 Issue: 3

Year: 2014 Volume: 102 Issue: 2

Year: 2014 Volume: 102 Issue: 1

Year: 2013 Volume: 101

Year: 2012 Volume: 100

Year: 2011 Volume: 99

Year: 2011 Volume: 98

Year: 2011 Volume: 97

Year: 2011 Volume: 96

Year: 2010 Volume: 95

Year: 2010 Volume: 94

Year: 2010 Volume: 93

Year: 2010 Volume: 92

Year: 2009 Volume: 91

Year: 2009 Volume: 90

Year: 2009 Volume: 89

Year: 2009 Volume: 88

Year: 2008 Volume: 87

Year: 2008 Volume: 86

Year: 2008 Volume: 85

Year: 2008 Volume: 84

Year: 2007 Volume: 81

Year: 2007 Volume: 80

Year: 2006 Volume: 79

Year: 2006 Volume: 78

Year: 2006 Volume: 77

Year: 2005 Volume: 73

Year: 2004 Volume: 70

Morphology, drug release, antibacterial, cell proliferation, and histology studies of chamomile-loaded wound dressing mats based on electrospun nanofibrous poly(É-caprolactone)/polystyrene blends.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Motealleh, Behrooz Zahedi, Payam Rezaeian, Iraj Moghimi, Morvarid Abdolghaffari, Amir Hossein Zarandi, Mohammad Amin
Description	Country affiliation: Iran Author Affiliation: Motealleh B ( Department of Polymer, School of Chemical Engineering, College of Engineering, University of Tehran, Tehran, Iran.)
Abstract	For the first time, it has been tried to achieve optimum conditions for electrospun poly(Îµ-caprolactone)/polystyrene (PCL/PS) nanofibrous samples as active wound dressings containing chamomile via D-optimal design approach. In this work, systematic in vitro and in vivo studies were carried out by drug release rate, antibacterial and antifungal evaluations, cell culture, and rat wound model along with histology observation. The optimized samples were prepared under the following electrospinning conditions: PCL/PS ratio (65/35), PCL concentration 9%(w/v), PS concentration 14%(w/v), distance between the syringe needle tip and the collector 15.5 cm, applied voltage 18 kV, and solution flow rate 0.46 mL h(-1) . The FE-SEM micrographs showed electrospun PCL/PS (65/35) nanofibrous sample containing 15% chamomile had a minimum average diameter (â¼175 nm) compared to the neat samples (â¼268 nm). The drug released resulted in a gradual and high amount of chamomile from the optimized PCL/PS nanofibrous sample (â¼70%) in respect to PCL and PS nanofibers after 48 h. This claim was also confirmed by antibacterial and antifungal evaluations in which an inhibitory zone with a diameter of about 7.6 mm was formed. The rat wound model results also indicated that the samples loaded with 15% chamomile extract were remarkably capable to heal the wounds up to 99 ± 0.5% after 14 days post-treatment periods. The adhesion of mesenchymal stem cells and their viability on the optimized samples were confirmed by MTT analysis. Also, the electrospun nanofibrous mats based on PCL/PS (65/35) showed a high efficiency in the wound closure and healing process compared to the reference sample, PCL/PS nanofibers without chamomile. Finally, the histology analysis revealed that the formation of epithelial tissues, the lack of necrosis and collagen fibers accumulation in the dermis tissues for the above optimized samples.
File Format	HTM / HTML
ISSN	15524973
Issue Number	5
Volume Number	102
e-ISSN	15524981
Journal	Journal of Biomedical Materials Research Part B: Applied Biomaterials
Language	English
Publisher	Wiley
Publisher Date	2014-07-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Biomedical engineering Anti-bacterial Agents Bandages Chamomile Chemistry Nanofibers Polyesters Polystyrenes Wounds And Injuries Therapy Animals Pharmacokinetics Pharmacology Candida Albicans Growth & Development Cell Line Disease Models, Animal Humans Rats Staphylococcus Aureus Journal Article
Content Type	Text
Resource Type	Article
Subject	Biomaterials Biomedical Engineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Electrospun Nanofibers/Nanofibrous Scaffolds Loaded with Silver Nanoparticles as Effective Antibacterial Wound Dressing Materials

Evaluation of poly ε-caprolactone electrospun nanofibers loaded with Hypericum perforatum extract as a wound dressing

Synthesis of Antibacterial Silver–Poly(ɛ-caprolactone)-Methacrylic Acid Graft Copolymer Nanofibers and Their Evaluation as Potential Wound Dressing

Physical and Antibacterial Properties of Peppermint Essential Oil Loaded Poly (ε-caprolactone) (PCL) Electrospun Fiber Mats for Wound Healing

Electrospun nanofibers synthesized from polymers incorporated with bioactive compounds for wound healing

Antibacterial Activity of Honey/Chitosan Nanofibers Loaded with Capsaicin and Gold Nanoparticles for Wound Dressing

Fabrication of Hybrid Nanofibers from Biopolymers and Poly (Vinyl Alcohol)/Poly (ε-Caprolactone) for Wound Dressing Applications

Electrospun polyvinyl alcohol-polyvinyl pyrrolidone nanofibrous membranes for interactive wound dressing application.

Co-electrospun nanofibrous mats loaded with bitter gourd (Momordica charantia) extract as the wound dressing materials: in vitro and in vivo study

Morphology, drug release, antibacterial, cell proliferation, and histology studies of chamomile-loaded wound dressing mats based on electrospun nanofibrous poly(É-caprolactone)/polystyrene blends.

Similar Documents

Electrospun Nanofibers/Nanofibrous Scaffolds Loaded with Silver Nanoparticles as Effective Antibacterial Wound Dressing Materials

Evaluation of poly ε-caprolactone electrospun nanofibers loaded with Hypericum perforatum extract as a wound dressing

Synthesis of Antibacterial Silver–Poly(ɛ-caprolactone)-Methacrylic Acid Graft Copolymer Nanofibers and Their Evaluation as Potential Wound Dressing

Physical and Antibacterial Properties of Peppermint Essential Oil Loaded Poly (ε-caprolactone) (PCL) Electrospun Fiber Mats for Wound Healing

Electrospun nanofibers synthesized from polymers incorporated with bioactive compounds for wound healing

Antibacterial Activity of Honey/Chitosan Nanofibers Loaded with Capsaicin and Gold Nanoparticles for Wound Dressing

Fabrication of Hybrid Nanofibers from Biopolymers and Poly (Vinyl Alcohol)/Poly (ε-Caprolactone) for Wound Dressing Applications

Electrospun polyvinyl alcohol-polyvinyl pyrrolidone nanofibrous membranes for interactive wound dressing application.

Co-electrospun nanofibrous mats loaded with bitter gourd (Momordica charantia) extract as the wound dressing materials: in vitro and in vivo study

Morphology, drug release, antibacterial, cell proliferation, and histology studies of chamomile-loaded wound dressing mats based on electrospun nanofibrous poly(É-caprolactone)/polystyrene blends.

Morphology, drug release, antibacterial, cell proliferation, and histology studies of chamomile-loaded wound dressing mats based on electrospun nanofibrous poly(É-caprolactone)/polystyrene blends.