NDLI: The use of antipsychotics among people treated with medications for dementia in residential aged care facilities.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Shin, Hee-Young Gadzhanova, Svetla Roughead, Elizabeth E. Ward, Michael B. Pont, Lisa G.
Description	Country affiliation: South Korea Author Affiliation: Shin HY ( Department of Biomedical Science,Chonnam National University Medical School,Gwangju,South Korea.); Gadzhanova S ( Quality Use of Medicines and Pharmacy Research Centre,Sansom Institute,School of Pharmacy and Medical Sciences,University of South Australia,Adelaide,Australia.); Roughead EE ( Quality Use of Medicines and Pharmacy Research Centre,Sansom Institute,School of Pharmacy and Medical Sciences,University of South Australia,Adelaide,Australia.); Ward MB ( Quality Use of Medicines and Pharmacy Research Centre,Sansom Institute,School of Pharmacy and Medical Sciences,University of South Australia,Adelaide,Australia.); Pont LG ( Australian Institute of heath Innovation,Macquarie University,Sydney,Australia.)
Abstract	BACKGROUND: Antipsychotic agents have limited efficacy for Behavioral and Psychological Symptoms of Dementia (BPSD) and there are concerns about their safety. Despite this, they are frequently used for the management of BPSD. This study aimed to assess the use of antipsychotics among people on anti-dementia medicines in Australian residential aged care facilities. METHODS: Data were obtained from an individual patient unit dose packaging database covering 40 residential aged care facilities in New South Wales, Australia. Residents supplied an anti-dementia medicine between July 2008 and June 2013 were included. Prevalence of concurrent antipsychotic use was established. Incident antipsychotic users between January 2009 and December 2011 were identified. We examined initial antipsychotic dose, maximum titrated doses, type and duration of antipsychotic use, and compared use with Australian guidelines. RESULTS: There were 291 residents treated with anti-dementia medicines, 129 (44%) of whom received antipsychotics concomitantly with an anti-dementia medicine. Among the 59 incident antipsychotic users, risperidone (73%) was the most commonly used antipsychotic agent. Amongst the risperidone initiators, 43% of patients had initial doses greater than 0.5 mg/day and 6% of patients exceeded 2.0 mg/day for their maximum dose. 53% of concomitant users received daily treatment for greater than six months. CONCLUSIONS: Our study using records of individual patient unit dose supply, which represents the intended medication consumption schedule, shows high rates of concurrent use of antipsychotics and anti-dementia medicines and long durations of use. The use of antipsychotics in patients with dementia needs to be carefully monitored to improve patient outcomes.
File Format	HTM / HTML
ISSN	10416102
Issue Number	6
Journal	International Psychogeriatrics
Volume Number	28
e-ISSN	1741203X
Language	English
Publisher	Cambridge University Press
Publisher Date	2016-06-01
Publisher Place	Great Britain (UK)
Access Restriction	Subscribed
Subject Keyword	Discipline Psychiatry Discipline Geriatrics
Content Type	Text
Resource Type	Article
Subject	Gerontology Clinical Psychology Geriatrics and Gerontology Psychiatry and Mental Health

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