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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Lode, H. M. Stahlmann, R. |
| Description | Author Affiliation: Lode HM ( Institut für klinische Pharmakologie und Toxikologie, Charité-Universitätsmedizin Berlin, Luisenstr. 7, 10177, Berlin, Deutschland, haloheck@zedat.fu-berlin.de.) |
| Abstract | Vaccinations are the most successful and cost-effective measures for prevention of infections. Important pathogens of respiratory tract infections (e.g. influenza viruses and pneumococci) can be effectively treated by vaccinations. The seasonal trivalent and recently now quadrivalent influenza vaccines include antigens from influenza A and B type viruses, which have to be modified annually oriented to the circulating strains. The effective protection by influenza vaccination varies considerably (too short protection time, mismatch); therefore, administration late in the year is the best approach (November/December). Two pneumococcal vaccines are recommended for adults: the over 30-year-old 23-valent polysaccharide vaccine (PPV23) and the 4-year-old 13-valent conjugate vaccine (PCV13). The immunological and clinical efficacy of PPV23 is controversially discussed; however, a moderate reduction of invasive pneumococcal infections is widely accepted. The PCV13 stimulates a T-cell response and has currently demonstrated its clinical efficacy in an impressive study (CAPiTA). The problem of PCV13 is the relatively limited coverage of only 47% of the currently circulating invasive pneumococcal serotypes. |
| File Format | HTM / HTML |
| ISSN | 00176192 |
| Issue Number | 9 |
| Volume Number | 63 |
| e-ISSN | 14330458 |
| Journal | HNO |
| Language | German |
| Publisher | Springer |
| Publisher Date | 2015-09-01 |
| Publisher Place | Germany |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Otolaryngology Influenza Vaccines Administration & Dosage Influenza, Human Prevention & Control Pneumococcal Vaccines Pneumonia, Pneumococcal Respiratory Tract Infections Drug Administration Schedule Humans English Abstract Journal Article |
| Alternative Title | Vaccinations in respiratory medicine |
| Content Type | Text |
| Resource Type | Article |
| Subject | Otorhinolaryngology |
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