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The ALPPS procedure for hepatocellular carcinoma.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Vennarecci, G. Laurenzi, A. Levi Sandri, G. B. Busi Rizzi, E. Cristofaro, M. Montalbano, M. Piselli, P. Andreoli, A. D'Offizi, G. Ettorre, G. M.
Description	Author Affiliation: Vennarecci G ( Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Rome, Lazio, Italy. Electronic address: gvennarecci@scamilloforlanini.rm.it.); Laurenzi A ( Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Rome, Lazio, Italy.); Levi Sandri GB ( Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Rome, Lazio, Italy.); Busi Rizzi E ( Division of Radiology, S. Camillo Hospital, Rome, Lazio, Italy.); Cristofaro M ( Division of Radiology, S. Camillo Hospital, Rome, Lazio, Italy.); Montalbano M ( Hepatology and Infectious Diseases Unit, National Institute for Infectious Diseases 'L. Spallanzani', Rome, Italy.); Piselli P ( Department of Epidemiology and Pre-Clinical Research, National Institute for Infectious Diseases 'L. Spallanzani', Rome, Italy.); Andreoli A ( Hepatology, S. Camillo Hospital, Rome, Lazio, Italy.); D'Offizi G ( Hepatology and Infectious Diseases Unit, National Institute for Infectious Diseases 'L. Spallanzani', Rome, Italy.); Ettorre GM ( Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Rome, Lazio, Italy.)
Abstract	BACKGROUND: The main limiting factor to major hepatic resections is the amount of the future liver remnant (FLR). Associating Liver Partition with Portal Vein Ligation for Staged Hepatectomy (ALPPS) is a procedure which induces a rapid hypertrophy of the FLR in patients with non-resectable liver tumours. METHODS: ALPPS is a surgical technique of in-situ splitting of the liver along the main portal scissura or the right side of the falciform ligament, in association with portal vein ligation in order to induce a rapid hypertrophy of the left FLR. RESULTS: The median FLR volume increase was 18.7% within one week after the first step and 38.6% after the second step. At the first step the median operating time was 300 min, blood transfusions were not required in any case, median blood loss was 150 cc. At the second step median operating time was 180 min, median blood loss was 50 cc, none of the patients required intra-operative blood. All patients are alive at a median follow up of 9 months. CONCLUSIONS: This novel strategy seems to be feasible even in the context of a cirrhotic liver, and demonstrates the capacity to reach a sufficient FLR within a shorter interval of time.
File Format	HTM / HTML
ISSN	07487983
Issue Number	8
Volume Number	40
e-ISSN	15322157
Journal	European Journal of Surgical Oncology (EJSO)
Language	English
Publisher	Elsevier
Publisher Date	2014-08-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline General Surgery Discipline Oncology Carcinoma, Hepatocellular Surgery Hepatectomy Methods Liver Neoplasms Liver Blood Supply Portal Vein Adult Aged Diagnosis Etiology Feasibility Studies Female Humans Ligation Pathology Magnetic Resonance Imaging Male Middle Aged Tomography, X-ray Computed Journal Article
Content Type	Text
Resource Type	Article
Subject	Surgery Oncology

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Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS): impact of the inter-stages course on morbi-mortality and implications for management.

Defining indications to ALPPS procedure: technical aspects and open issues.

Case Report: Robotic ALPPS Procedure for Hepatocellular Carcinoma in the Right Lobe of the Liver

Rapid improvement in liver volume induced by portal vein ligation and staged hepatectomy: the ALPPS procedure.

Large hepatocellular carcinoma conquered by ALPPS: a case report

Our initial experience with ALPPS technique: encouraging results.

Outflow modulation to target liver regeneration: something old, something new.

Is 'small for size syndrome' a relatively new complication after the ALPPS procedure?

Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS): short-term outcome, functional changes in the future liver remnant, and tumor growth activity.

The ALPPS procedure for hepatocellular carcinoma.

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Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS): impact of the inter-stages course on morbi-mortality and implications for management.

Defining indications to ALPPS procedure: technical aspects and open issues.

Case Report: Robotic ALPPS Procedure for Hepatocellular Carcinoma in the Right Lobe of the Liver

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