NDLI: Accuracy of noninvasive haemoglobin measurement by pulse oximetry depends on the type of infusion fluid. (Journal: European Journal of Anaesthesiology Volume: 29 Issue: 12)

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Bergek, Christian Zdolsek, Joachim H. Hahn, Robert G.
Description	Country affiliation: Sweden Author Affiliation: Bergek C ( Section for Anaesthesia, Faculty of Health Sciences, Linköping University, Linköping, Sweden.)
Abstract	CONTEXT: Measurement of blood haemoglobin concentration by pulse oximetry could be of value in determining when erythrocytes should be transfused during surgery, but the effect of infusion fluids on the results is unclear. OBJECTIVE: To study the effect of crystalloid and colloid fluid on the accuracy (bias) and precision of pulse oximetry haemoglobin estimation to indicate the venous haemoglobin concentration in volunteers. DESIGN: Open interventional crossover study. SETTING: Single university hospital. PARTICIPANTS: Ten male volunteers aged 18-28 (mean 22) years. INTERVENTIONS: Each volunteer underwent three infusion experiments on separate days and in random order. The infusions were Ringer's acetate (20 mlâkg), hydroxyethyl starch 130/0.4 (10 mlâkg) and a combination of both. RESULTS: At the end of the infusions of Ringer's acetate, pulse oximetry haemoglobin concentration had decreased more than the true haemoglobin concentration (15 vs. 8%; P < 0.005; n = 10) whereas starch solution decreased pulse oximetry haemoglobin concentration less than true haemoglobin concentration (7 vs. 11%; P < 0.02; n = 20). The same differences were seen when the fluids were infused separately and when they were combined. The overall difference between all 956 pairs of pulse oximetry haemoglobin concentration and true haemoglobin concentrations (the bias) averaged only -0.7 gâl whereas the 95% prediction interval was wide, ranging from -24.9 to 23.7 gâl. In addition to the choice of infusion fluid, the bias was strongly dependent on the volunteer (each factor, P < 0.001). CONCLUSION: The bias of measuring haemoglobin concentration by pulse oximetry is dependent on whether a crystalloid or a colloid fluid is infused. Trial registration ClinicalTrials identifier: NCT01195025.
Related Links	http://journals.lww.com/ejanaesthesiology/Fulltext/2012/12000/Accuracy_of_noninvasive_haemoglobin_measurement_by.8.aspx
File Format	HTM / HTML
ISSN	02650215
Issue Number	12
Volume Number	29
e-ISSN	13652346
Journal	European Journal of Anaesthesiology
Language	English
Publisher	Lippincott Williams & Wilkins
Publisher Date	2012-12-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Anesthesiology Hemoglobins Analysis Oximetry Methods Adolescent Adult Colloids Chemistry Cross-over Studies Crystallization Erythrocyte Transfusion Metabolism Humans Isotonic Solutions Male Monitoring, Intraoperative Perfusion Reproducibility Of Results Young Adult Clinical Trial Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Anesthesiology and Pain Medicine

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Accuracy of noninvasive haemoglobin measurement by pulse oximetry depends on the type of infusion fluid. (Journal: European Journal of Anaesthesiology Volume: 29 Issue: 12)

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