| Content Provider |
World Health Organization (WHO)-Global Index Medicus |
| Author |
Wang, Lei Wang, Xiao-Rong Liu, Jin Chen, Chu-Xian Liu, Yuan Wang, Wei-Na |
| Description |
Author Affiliation: Wang L ( Institute of Pharmaceutical Research, South China Normal University, Guangzhou, 510631, People's Republic of China.); Wang XR ( Key Laboratory of Ecology and Environmental Science in Guangdong Higher Education, Guangdong Provincial Key Laboratory for Healthy and Safe Aquaculture, College of Life Science, South China Normal University, Guangzhou, 510631, People's Republic of China.); Liu J ( Key Laboratory of Ecology and Environmental Science in Guangdong Higher Education, Guangdong Provincial Key Laboratory for Healthy and Safe Aquaculture, College of Life Science, South China Normal University, Guangzhou, 510631, People's Republic of China.); Chen CX ( Key Laboratory of Ecology and Environmental Science in Guangdong Higher Education, Guangdong Provincial Key Laboratory for Healthy and Safe Aquaculture, College of Life Science, South China Normal University, Guangzhou, 510631, People's Republic of China.); Liu Y ( Key Laboratory of Ecology and Environmental Science in Guangdong Higher Education, Guangdong Provincial Key Laboratory for Healthy and Safe Aquaculture, College of Life Science, South China Normal University, Guangzhou, 510631, People's Republic of China.); Wang WN ( Key Laboratory of Ecology and Environmental Science in Guangdong Higher Education, Guangdong Provincial Key Laboratory for Healthy and Safe Aquaculture, College of Life Science, South China Normal University, Guangzhou, 510631, People's Republic of China.) |
| Abstract |
With the destruction of the ecological environment, shrimp cultivation in China has been seriously affected by outbreaks of infectious diseases. Rab, which belong to small GTPase Ras superfamily, can regulate multiple steps in eukaryotic vesicle trafficking including vesicle budding, vesicle tethering, and membrane fusion. Knowledge of Rab in shrimp is essential to understanding regulation and detoxification mechanisms of environmental stress. In this study, we analyzed the functions of Rab from the Pacific white shrimp, Litopenaeus vannamei. Full-length cDNA of Rab was obtained, which was 751 bp long, with open reading frame encoding 206 amino acids. In this study, for the first time, the gene expression of Rab of L. vannamei was analyzed by quantitative real-time PCR after exposure to five kinds of environmental stresses (bacteria, pH, Cd, salinity and low temperature). The results demonstrate that Rab is sensitive and involved in bacteria, pH, and Cd stress responses and Rab is more sensitive to bacteria than other stresses. Therefore we infer that Rab may have relationship with the anti-stress mechanism induced by environment stress in shrimp and Rab could be used as critical biomarkers for environmental quality assessment. |
| File Format |
HTM / HTML |
| ISSN |
09639292 |
| Issue Number |
7-8 |
| Volume Number |
24 |
| e-ISSN |
15733017 |
| Journal |
Ecotoxicology |
| Language |
English |
| Publisher |
Springer |
| Publisher Date |
2015-10-01 |
| Publisher Place |
United States |
| Access Restriction |
One Nation One Subscription (ONOS) |
| Subject Keyword |
Discipline Ecology Discipline Environmental Health Discipline Toxicology Arthropod Proteins Genetics Metabolism Penaeidae Stress, Physiological Amino Acid Sequence Animals Base Sequence Cloning, Molecular Dna, Complementary Hydrogen-ion Concentration Molecular Sequence Data Rna, Messenger Subtractive Hybridization Techniques Ras Proteins Journal Article Research Support, Non-u.s. Gov't |
| Content Type |
Text |
| Resource Type |
Article |
| Subject |
Health, Toxicology and Mutagenesis Medicine Toxicology Management, Monitoring, Policy and Law |
