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Assessing the acute hazards of zinc oxide nanomaterials to Lumbriculus variegatus.

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Assessing the acute hazards of zinc oxide nanomaterials to Lumbriculus variegatus.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	O'Rourke, Shona Stone, Vicki Stolpe, Björn Fernandes, Teresa F.
Description	Country affiliation: United kingdom Author Affiliation: O'Rourke S ( The School of Life Sciences, Heriot Watt University, Riccarton, Edinburgh, EH14 4AS, UK.)
Abstract	These studies were undertaken in order to propose and test new methods for the assessment of the acute hazard of ZnO nanoparticles (NPs) to the sediment dwelling oligochaete worm Lumbriculus variegatus. In order to support the developing nanotechnology sector, comprehensive studies must be conducted to assess the toxicity of nanomaterials (NMs) using environmentally relevant organisms. An important part of such studies will entail characterising and understanding the physicochemical properties of these NMs. In this study NMs were characterised using a range of techniques, in order to assess agglomeration/aggregation and dissolution. Toxicology studies included a behavioural assay and the measurement of oxidative stress. When considering the toxicology results from all experiments using L. variegatus within this paper ZnO NPs (0-10 mg/l) were found to cause acute toxicity in terms of behavioural response, but not to cause acute oxidative stress in terms of glutathione (GSH) depletion. It was also concluded that the behavioural assay and the GSH assay were both suitable techniques for assessing the acute hazard of NMs to L. variegatus.
File Format	HTM / HTML
ISSN	09639292
Issue Number	6
Volume Number	24
e-ISSN	15733017
Journal	Ecotoxicology
Language	English
Publisher	Springer
Publisher Date	2015-08-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Ecology Discipline Environmental Health Discipline Toxicology Metal Nanoparticles Toxicity Oligochaeta Drug Effects Toxicity Tests, Acute Water Pollutants, Chemical Zinc Oxide Animals Locomotion Oxidative Stress Soil Pollutants Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Health, Toxicology and Mutagenesis Medicine Toxicology Management, Monitoring, Policy and Law

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Assessing the acute hazards of zinc oxide nanomaterials to Lumbriculus variegatus

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