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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Schliephake, Henning Drewes, Mona Mihatovic, Ilja Schwarz, Frank Becker, Jürgen Iglhaut, Gerhard |
| Description | Country affiliation: Germany Author Affiliation: Schliephake H ( Department of Oral and Maxillofacial Surgery, George-Augusta-University, Göttingen, Germany.) |
| Abstract | AIM: The aim of the present study was to evaluate bone formation in vertical ridge augmentations using particulate bone grafting material stabilized by a resorbable polymer. MATERIAL AND METHODS: Three vertical defects were created in the maxillary alveolar ridge of six Beagle dogs 3 months after the removal of all premolars. One defect in each dog was filled with tricalciumphosphate/hydroxylapatite (TCP/HA) grafting material and stabilized using a poloxamer hydrogel (test group). Defects filled with grafting material only and covered with a collagen membrane as well as empty defects served as controls (controls 1 & 2). Bone formation in the defects was evaluated after 14 weeks of healing using histomorphometry on undecalcified thick-section specimens. RESULTS: There was no difference between the test group and the controls with respect to the amount of newly formed bone, percentage of bone fill, and bone density. The mean maximum bone height within the augmented area was the only parameter that was significantly higher in the test group compared with empty defects. The use of the poloxamer gel did not result in a better preservation of ridge shape compared with the group of augmentations covered with a collagen membrane. CONCLUSIONS: The use of a poloxamer gel for the stabilization of particulate bone grafting material in vertical ridge augmentations had no advantage compared with coverage of grafting materials with a collagen membrane. |
| File Format | HTM / HTML |
| ISSN | 09057161 |
| Issue Number | 4 |
| Volume Number | 25 |
| e-ISSN | 16000501 |
| Journal | Clinical Oral Implants Research |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2014-04-01 |
| Publisher Place | Denmark |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Dentistry Discipline General Surgery Alginates Pharmacology Alveolar Ridge Augmentation Methods Bone Substitutes Calcium Phosphates Durapatite Glucuronates Hydrogels Osteogenesis Poloxamer Animals Collagen Dogs Drug Combinations Maxilla Pilot Projects Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Oral Surgery |
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