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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Dienz, Oliver Rincon, Mercedes |
| Description | Country affiliation: United States Author Affiliation: Dienz O ( Department of Medicine/Immunobiology program, Given Medical Building D305, University of Vermont, 89 Beaumont Avenue, Burlington, VT 05405, USA.) |
| Abstract | Cytokines have long been known to profoundly influence the adaptive immune response by determining CD4 T cell differentiation. Although IL-6 has been initially characterized as a B cell growth factor and inducer of antibody production research from our lab and others has revealed over the last years that IL-6 also plays a significant role in CD4 T cell differentiation. This review highlights the variety of ways in which IL-6 affects CD4 effector functions and how this may contribute to different types of diseases. |
| File Format | HTM / HTML |
| ISSN | 15216616 |
| e-ISSN | 15217035 |
| DOI | 10.1016/j.clim.2008.08.018 |
| Journal | Clinical Immunology |
| Issue Number | 1 |
| Volume Number | 130 |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2009-01-01 |
| Publisher Place | United States |
| Access Restriction | Open |
| Subject Keyword | Discipline Immunology Cd4-positive T-lymphocytes Immunology Interleukin-6 Animals Cytology Metabolism Cell Differentiation Cell Survival Receptors, Interleukin-6 Signal Transduction Research Support, N.i.h., Extramural |
| Content Type | Text |
| Resource Type | Article |
| Subject | Immunology and Allergy Immunology |
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