NDLI: miRNA in systemic lupus erythematosus.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Amarilyo, Gil La Cava, Antonio
Description	Country affiliation: United States Author Affiliation: Amarilyo G ( Department of Medicine at University of California Los Angeles, CA 90095-1670, USA. gamarilyo@mednet.ucla.edu)
Abstract	Since their recent discovery, the small noncoding RNA known as microRNAs (miRNA) have been reported to play a major role in the physiological control of gene expression and in the pathogenesis of malignant, infectious, and autoimmune disorders. In systemic lupus erythematosus (SLE), an autoimmune disease characterized by the presence of autoantibodies to multiple antigens, the role of miRNA as post-transcriptional regulators of different aspects of the disease process has recently emerged. This article reviews the pertinent literature and mechanisms of action of miRNA that have so far been associated with the pathogenesis of SLE.
File Format	HTM / HTML
ISSN	15216616
Issue Number	1
Journal	Clinical Immunology
Volume Number	144
e-ISSN	15217035
Language	English
Publisher	Elsevier
Publisher Date	2012-07-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Immunology Lupus Erythematosus, Systemic Genetics Micrornas Animals Humans Journal Article Review
Content Type	Text
Resource Type	Article
Subject	Immunology and Allergy Immunology

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miRNA in systemic lupus erythematosus.