NDLI: Spinal cerebrospinal fluid volume in healthy elderly individuals.

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Spinal cerebrospinal fluid volume in healthy elderly individuals.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Edsbagge, M. Starck, G. Zetterberg, H. Ziegelitz, D. Wikkelso, C.
Description	Country affiliation: Sweden Author Affiliation: Edsbagge M ( Department of Clinical Neuroscience and Rehabilitation, Hydrocephalus Research Unit, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden. mikael.edsbagge@neuro.gu.se)
Abstract	The amount of spinal cerebrospinal fluid (CSF) could be of importance for the understanding of CSF dynamics, CSF biomarker analyses as well as for the amount and effect of anaesthesia using intrathecally administered drugs. However, knowledge of spinal CSF volumes is scarce. The main purpose of this article is to present data on spinal CSF volumes. In total, 22 healthy individuals aged between 64 and 76 years underwent MR imaging with a 3D balanced turbo field echo pulse sequence, which provided high contrast between spinal cord, CSF and the extradural surroundings. The entire spinal CSF volume, the cervical, thoracic, and lumbosacral CSF volumes and the spinal cord volume were calculated. The total spinal CSF volume was 81 ± 13 ml (range 52-103 ml). The amount of CSF in the cervical region was 19 ± 4 ml, in the thoracic region 38 ± 8 and in the lumbosacral region 25 ± 7 ml. There was no difference between genders nor was there any correlation with height. The volume of the spinal cord was 20 ± 3 ml. The results present new magnetic resonance imaging-based data on the spinal CSF volume in healthy elderly individuals.
File Format	HTM / HTML
ISSN	08973806
Issue Number	6
Volume Number	24
e-ISSN	10982353
Journal	Clinical Anatomy
Language	English
Publisher	Wiley-Liss
Publisher Date	2011-09-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Physiology Discipline Anatomy Cerebrospinal Fluid Aged Female Humans Hydrocephalus, Normal Pressure Diagnosis Magnetic Resonance Imaging Male Reference Values Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Anatomy Histology

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