NDLI: Intravitreal triamcinolone for persistent cystoid macular oedema in eyes with quiescent uveitis.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Maca, Saskia M. Abela-Formanek, Claudette Kiss, Christopher G. Sacu, Stefan G. Benesch, Thomas Barisani-Asenbauer, Talin
Description	Country affiliation: Austria Author Affiliation: Maca SM ( Medical University Vienna, Department of Ophthalmology & Optometry, Vienna, Austria.)
Abstract	BACKGROUND: To determine the outcome following injections of triamcinolone acetate (IVTA) in the treatment of persistent cystoid macular oedema (CMO) in quiescent, non-infectious uveitis. METHODS: Retrospective analysis of patients with inactive uveitis requiring/not requiring immunosuppressive therapy who received IVTA because of chronic CMO refractory to previous systemic steroids. Number of IVTA (re-)treatments, distance visual acuity, near visual acuity, mean foveal thickness, intraocular pressure, duration of CMO, type of uveitis and systemic therapy were assessed previous to and 1, 4, 12 weeks following each IVTA treatment. RESULTS: Between March 2003 and May 2006, 24 eyes of 18 patients received between one and three IVTA injections. A resolution of chronic CMO was observed in 7/24 eyes (29.2%, 5 eyes after single injection of IVTA, 1 eye each after two and three injections of IVTA), a significant increase in distance visual acuity in 9/24 eyes (37.5%; 5 eyes with resolution of CMO, 4 eyes despite persistent CMO) and in near visual acuity in 13/24 eyes (54.6%; 6 eyes with resolution of CMO, 7 eyes despite persistent CMO). CONCLUSIONS: IVTA might be considered as a treatment for patients with chronic CMO when persistent despite previous systemic steroid therapy. Even patients without sustained resolution of CMO after IVTA might benefit in terms of transiently increasing visual acuity, but progression of cataract and rise in intraocular pressure limit repeatability.
File Format	HTM / HTML
ISSN	14426404
Issue Number	4
Volume Number	37
e-ISSN	14429071
Journal	Clinical & Experimental Ophthalmology
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2009-05-01
Publisher Place	Australia
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Ophthalmology Glucocorticoids Therapeutic Use Macular Edema Drug Therapy Triamcinolone Acetonide Uveitis Cataract Chemically Induced Chronic Disease Female Follow-up Studies Adverse Effects Humans Injections Intraocular Pressure Drug Effects Etiology Physiopathology Male Middle Aged Retrospective Studies Treatment Outcome Complications Visual Acuity Vitreous Body Journal Article
Content Type	Text
Resource Type	Article
Subject	Ophthalmology

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