NDLI: Cataract and quality of life in patients with glaucoma.

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Cataract and quality of life in patients with glaucoma.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Skalicky, Simon E. Martin, Keith R. Fenwick, Eva Crowston, Jonathan G. Goldberg, Ivan McCluskey, Peter
Description	Country affiliation: Australia Author Affiliation: Skalicky SE ( Discipline of Ophthalmology, University of Sydney, Sydney, New South Wales, Australia.); Martin KR ( Centre for Eye Research Australia, University of Melbourne, Melbourne, Victoria, Australia.); Fenwick E ( Department of Ophthalmology, Addenbrooke's Hospital, Cambridge, UK.); Crowston JG ( Departments of Ophthalmology and Surgery, Royal Melbourne Hospital, University of Melbourne.); Goldberg I ( Department of Ophthalmology, Addenbrooke's Hospital, Cambridge, UK.); McCluskey P ( Cambridge NIHR Biomedical Research Centre, University of Cambridge, Cambridge, UK.)
Abstract	BACKGROUND: To assess the impact of cataract on quality of life (QoL) for patients with glaucoma. DESIGN: Cross-sectional study. PARTICIPANTS: Two hundred forty-two patients with mild (n = 67), moderate (n = 80) or severe (n = 45) glaucoma and 50 controls (glaucoma suspects). Patients with cataract of any severity were included. METHODS: The following data were collected: sociodemographic information, phakic/pseudophakic status, cataract grade according to the Lens Opacities Classification System (LOCS) III, visual acuity and visual field test parameters. Glaucoma severity was stratified according to binocular visual field loss. Visually significant cataract was defined as: LOCS III criteria nuclear cataract ≥3/6.9, cortical cataract ≥3/5.9 or posterior subcapsular cataract ≥2/5.9. MAIN OUTCOME MEASURES: Patients' QoL was measured using Rasch-transformed scores from the Glaucoma Activity Limitation-9 (GAL-9) questionnaire. Multiple linear regression models were used to determine the association between cataract and GAL-9 (logit) score. RESULTS: Fifty-six (23.1%) patients had at least one visually significant cataract. At least one visually significant cataract (standardized coefficient [ß] 1.19, 95% confidence interval 1.04-1.34, P = 0.011) and poor visual field index (better eye) (ß 1.47, 95% confidence interval 1.36-1.88, P < 0.001) were independently associated with worse GAL-9 score. CONCLUSIONS: Cataract influences glaucoma-related QoL among glaucoma patients of all severity levels and is an important cause of potentially reversible visual impairment among glaucoma patients. The Rasch-analysed GAL-9 questionnaire is a useful metric to quantify visual disability related to cataract in glaucoma patients.
File Format	HTM / HTML
ISSN	14426404
Issue Number	4
Volume Number	43
e-ISSN	14429071
Journal	Clinical & Experimental Ophthalmology
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2015-05-01
Publisher Place	Australia
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Ophthalmology Cataract Psychology Glaucoma, Open-angle Quality Of Life Vision Disorders Visually Impaired Persons Aged Aged, 80 And Over Physiopathology Cross-sectional Studies Female Classification Humans Male Middle Aged Risk Factors Questionnaires Visual Acuity Physiology Visual Field Tests Visual Fields Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Ophthalmology

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