NDLI: 2-azapurine nucleosides: synthesis, properties, and base pairing of oligonucleotides.

Please wait, while we are loading the content...

Oligonucleotides with sugars other than ribo- and 2'-deoxyribofuranose in the backbone: the solution structures determined by NMR in the context of the 'Etiology of nucleic acids' project of Albert Eschenmoser.

The biosynthesis of branched dialkylpyrazines in myxobacteria.

2-azapurine nucleosides: synthesis, properties, and base pairing of oligonucleotides.

An alternative standard for Trolox-equivalent antioxidant-capacity estimation based on thiol antioxidants. Comparative 2,2'-azinobis[3-ethylbenzothiazoline-6-sulfonic acid] decolorization and rotational viscometry study regarding hyaluronan degradation.

Chemical and biological aspects of marine sponges of the genus Xestospongia.

Volatile methyl esters of medium chain length from the bacterium Chitinophaga Fx7914.

Early-season headspace volatiles from apple and their effect on the apple blossom weevil Anthonomus pomorum.

A survey of phytotoxic microbial and plant metabolites as potential natural products for pest management.

Phytochemical analysis and in vitro free-radical-scavenging activities of the essential oils from leaf and fruit of Melaleuca leucadendra L.

Bioactive triterpenoids from Kadsura heteroclita.

Regulation of the 5-HT3A receptor-mediated current by alkyl 4-hydroxybenzoates isolated from the seeds of Nelumbo nucifera.

Anti-tumor-initiating effects of spiro-biflavonoids from Abies sachalinensis.

Volatile composition screening of Salix spp. nectar honey: benzenecarboxylic acids, norisoprenoids, terpenes, and others.

Year: 2010 Volume: 7 Issue: 8

Year: 2010 Volume: 7 Issue: 7

Year: 2010 Volume: 7 Issue: 6

Year: 2010 Volume: 7 Issue: 5

Year: 2010 Volume: 7 Issue: 4

Year: 2010 Volume: 7 Issue: 3

Year: 2010 Volume: 7 Issue: 2

Year: 2010 Volume: 7 Issue: 1

Year: 2009 Volume: 6

Year: 2008 Volume: 5

Year: 2007 Volume: 4

2-azapurine nucleosides: synthesis, properties, and base pairing of oligonucleotides.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Budow, Simone Seela, Frank
Description	Author Affiliation: Budow S ( Laboratory of Bioorganic Chemistry and Chemical Biology, Center for Nanotechnology, Heisenbergstrasse 11, Münster.)
Abstract	This review deals with 2-azapurine (imidazo[4,5-d] [1,2,3]triazine) nucleosides and closely related analogs. Different routes are described to yield the desired target compounds, including a sequence of ring-opening and ring-closure reactions performed on purine nucleosides or direct glycosylation of a 2-azapurine nucleobase with a sugar halide. Further, physical and spectroscopic properties of 2-azapurine nucleosides are discussed, including fluorescence, (13)C-NMR data, single-crystal X-ray analyses, and conformation studies on selected compounds; new biological data are presented. The second part of this review is dedicated to oligonucleotides containing 2-azapurines, including building-block (phosphoramidite) preparation and their use in solid-phase oligonucleotide synthesis. Base-pairing properties of 2-azapurine nucleosides as surrogates of canonical constituents of DNA were evaluated.
File Format	HTM / HTML
ISSN	16121872
Issue Number	9
Volume Number	7
e-ISSN	16121880
Journal	Chemistry & Biodiversity
Language	English
Publisher	Wiley
Publisher Date	2010-09-01
Publisher Place	Switzerland
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Biochemistry Discipline Chemistry Aza Compounds Chemical Synthesis Base Pairing Oligonucleotides Purine Nucleosides Antineoplastic Agents Chemistry Pharmacology Antiviral Agents Carbohydrate Conformation Magnetic Resonance Spectroscopy Journal Article Research Support, Non-u.s. Gov't Review
Content Type	Text
Resource Type	Article
Subject	Chemistry Medicine Molecular Biology Biochemistry Molecular Medicine Bioengineering

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Synthesis of 3'-C-hydroxymethyl-substituted pyrimidine and purine nucleosides as potential anti-hepatitis C virus (HCV) agents.

Synthesis of novel 6-azapyrimidine acyclic nucleoside analogues and antiviral evaluation.

Synthesis of novel bicyclic nucleosides with 3,6-anhydro sugar moiety.

A novel synthesis of antiviral nucleoside phosphoramidate and thiophosphoramidate prodrugs via nucleoside H-phosphonamidates.

Synthesis and biological evaluation of novel selenonucleosides.

Synthesis and in vitro antiviral activities of [(dihydrofuran-2-yl)oxy]methyl-phosphonate nucleosides with 2-substituted adenine as base.

Synthesis and antiviral evaluation of novel 2,3-dihydroxypropyl nucleosides from 2- and 4-thiouracils.

Aza-polycyclic aromatic hydrocarbons from Saruma henryi.

5-Aza-7-deazaguanine-Isoguanine and Guanine-Isoguanine Base Pairs in Watson-Crick DNA: The Impact of Purine Tracts, Clickable Dendritic Side Chains, and Pyrene Adducts.

2-azapurine nucleosides: synthesis, properties, and base pairing of oligonucleotides.

Similar Documents

Synthesis of 3'-C-hydroxymethyl-substituted pyrimidine and purine nucleosides as potential anti-hepatitis C virus (HCV) agents.

Synthesis of novel 6-azapyrimidine acyclic nucleoside analogues and antiviral evaluation.

Synthesis of novel bicyclic nucleosides with 3,6-anhydro sugar moiety.

A novel synthesis of antiviral nucleoside phosphoramidate and thiophosphoramidate prodrugs via nucleoside H-phosphonamidates.

Synthesis and biological evaluation of novel selenonucleosides.

Synthesis and in vitro antiviral activities of [(dihydrofuran-2-yl)oxy]methyl-phosphonate nucleosides with 2-substituted adenine as base.

Synthesis and antiviral evaluation of novel 2,3-dihydroxypropyl nucleosides from 2- and 4-thiouracils.

Aza-polycyclic aromatic hydrocarbons from Saruma henryi.

5-Aza-7-deazaguanine-Isoguanine and Guanine-Isoguanine Base Pairs in Watson-Crick DNA: The Impact of Purine Tracts, Clickable Dendritic Side Chains, and Pyrene Adducts.

2-azapurine nucleosides: synthesis, properties, and base pairing of oligonucleotides.