NDLI: Recurrence risk after noncardioembolic mild ischemic stroke in a Japanese population.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Kono, Yuji Yamada, Sumio Kamisaka, Kenta Araki, Amane Fujioka, Yusuke Yasui, Keizo Hasegawa, Yasuhiro Koike, Yasuo
Spatial Coverage	Japan
Description	Country affiliation: Japan Author Affiliation: Kono Y ( Program in Physical and Occupational Therapy, Nagoya University Graduate School of Medicine, Japan.)
Abstract	BACKGROUND AND PURPOSE: This study aimed to identify the recurrence rate and risk factors or clinical variables predictive of vascular events after mild ischemic stroke (IS). METHODS: From December 2006 to September 2007, patients with acute IS with a modified Rankin Scale of 0â¼1 were consecutively enrolled in this study. Variables including sex, family history of vascular disease, age, height, weight, stroke subtype, blood pressure, lipid profile, fasting glucose, HbA1c, smoking, alcohol consumption, exercise habits, waist circumference, ankle-brachial pressure index, salt intake and physical activity were assessed. The primary outcome was stroke recurrence or other vascular events such as myocardial infarction, angina pectoris, and peripheral artery disease. Survival curves were calculated by Kaplan-Meier survival analysis, and hazard ratios for recurrence were determined by univariate and multivariate Cox proportional hazards regression models. RESULTS: A total of 102 mild IS patients (78 men and 24 women, mean age 64 years) were successfully followed for 3 years. Of those 102 patients, 25 (24.5%) had stroke recurrence, and 4 (3.9%) had a coronary event. Among the variables studied, abnormal ankle-brachial pressure index, metabolic syndrome, stroke subtypes, salt intake and poor lifestyle management were significant independent predictors of stroke recurrence or cardiovascular events. CONCLUSIONS: In mild IS patients within 3 years after onset, not only pathophysiological factors but also lifestyle factors can aid in the identification of patients at high risk for recurrence.
File Format	HTM / HTML
ISSN	10159770
e-ISSN	14219786
Journal	Cerebrovascular Diseases
Issue Number	4
Volume Number	31
Language	English
Publisher	Karger
Publisher Date	2011-01-01
Publisher Place	Switzerland
Access Restriction	Open
Subject Keyword	Discipline Vascular Diseases Discipline Cardiology Asian Continental Ancestry Group Statistics & Numerical Data Brain Ischemia Ethnology Stroke Diagnosis Mortality Physiopathology Chi-square Distribution Disability Evaluation Epidemiology Kaplan-meier Estimate Life Style Magnetic Resonance Imaging Proportional Hazards Models Recurrence Risk Assessment Risk Factors Severity Of Illness Index Time Factors
Content Type	Text
Resource Type	Article
Subject	Neurology Neurology (clinical) Cardiology and Cardiovascular Medicine

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