NDLI: Ultrasound Guided High Intensity Focused Ultrasound for malignant tumors: The Spanish experience of survival advantage in stage III and IV pancreatic cancer.

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The effect of ultrasound on particle size, color, viscosity and polyphenol oxidase activity of diluted avocado puree.

Evaluation of short cycles of ultrasound application in nanoemulsions to obtain nanocapsules.

A robust super-paramagnetic TiO2:Fe3O4:Ag nanocomposite with enhanced photo and bio activities on polyester fabric via one step sonosynthesis.

Optimization of ultrasonic-assisted extraction of total carotenoids from peach palm fruit (Bactris gasipaes) by-products with sunflower oil using response surface methodology.

Lipase catalysed synthesis of cetyl oleate using ultrasound: Optimisation and kinetic studies.

Effect of high power low frequency ultrasound processing on the stability of lycopene.

Influence of postharvest ultrasounds treatments on tomato (Solanum lycopersicum, cv. Zinac) quality and microbial load during storage.

Ultrasound intensification suppresses the need of methanol excess during the biodiesel production with Lipozyme TL-IM.

The decomposition of protoporphyrin IX by ultrasound is dependent on the generation of hydroxyl radicals.

Synergistic degradation of chitosan by impinging stream and jet cavitation.

The comparison of sonochemistry, electrochemistry and sonoelectrochemistry techniques on decolorization of C.I Reactive Blue 49.

Sonocatalytic decolorization of textile wastewater using synthesized Î³-FeOOH nanoparticles.

Effect of ultrasonic waves on the stability of all-trans lutein and its degradation kinetics.

Use of Adaptive Focused Acoustics™ ultrasound in controlling liposome formation.

Ultrasound assisted combustion synthesis of TiC in Al-Ti-C system.

The principles of ultrasound and its application in freezing related processes of food materials: A review.

Ultrasound Guided High Intensity Focused Ultrasound for malignant tumors: The Spanish experience of survival advantage in stage III and IV pancreatic cancer.

Feasibility study of high intensity focused ultrasound (HIFU) for the treatment of hydatid cysts of the liver.

Minimal invasive treatments for liver malignancies.

High-intensity focused ultrasound (HIFU) for adenomyosis: Two-year follow-up results.

High-intensity focused ultrasound ablation for diffuse uterine leiomyomatosis: A case report.

A review of high intensity focused ultrasound in relation to the treatment of renal tumours and other malignancies.

Ultrasound-guided high-intensity focused ultrasound treatment for uterine fibroid & adenomyosis: A single center experience from the Republic of Korea.

The theoretical basis of minimally-invasive and non-invasive medicine: Treatments--Minimize harm to patients.

Safety of ultrasound-guided ultrasound ablation for uterine fibroids and adenomyosis: A review of 9988 cases.

Treatment of liver alveococcosis with high-intensity focused ultrasound.

Humane accomplishment of physicians and the philosophy of minimally-invasive and noninvasive medicine: A perspective.

Preoperative ultrasound ablation for borderline resectable pancreatic cancer: A report of 30 cases.

Using microbubble sonographic contrast agent to enhance the effect of high intensity focused ultrasound for the treatment of uterine fibroids.

Enzyme-catalyzed synthesis and kinetics of ultrasonic-assisted biodiesel production from waste tallow.

Simultaneous sonosynthesis and sonofabrication of N-doped ZnO/TiO2 core-shell nanocomposite on wool fabric: Introducing various properties specially nano photo bleaching.

Ultrasound pressure distributions generated by high frequency transducers in large reactors.

One-pot sonochemical synthesis of ferrocenyl derivatives via a three-component reaction in aqueous media.

Ultrasound-assisted bioethanol production from waste newspaper.

Effects of multi-frequency power ultrasound on the enzymolysis of corn gluten meal: Kinetics and thermodynamics study.

Optimization of ultrasonic assisted continuous production of biodiesel using response surface methodology.

Effects of ultrasound pretreatment on the characteristic evolutions of drinking water treatment sludge and its impact on coagulation property of sludge recycling process.

In situ observation and analysis of ultrasonic capillary effect in molten aluminium.

Experimental study on the disinfection efficiencies of a continuous-flow ultrasound/ultraviolet baffled reactor.

Understanding the effect of novel approaches based on ultrasound on sensory profile of orange juice.

Free radical generation induced by ultrasound in red wine and model wine: An EPR spin-trapping study.

Ultrasound versus microwave as green processes for extraction of rosmarinic, carnosic and ursolic acids from rosemary.

New method to enhance the extraction yield of rutin from Sophora japonica using a novel ultrasonic extraction system by determining optimum ultrasonic frequency.

Degradation of magenta dye using different approaches based on ultrasonic and ultraviolet irradiations: Comparison of effectiveness and effect of additives for intensification.

Effect of novel ultrasound based processing on the nutrition quality of different fruit and vegetable juices.

Impact of pulsed ultrasound on bacteria reduction of natural waters.

Critical factors in sonochemical degradation of fumaric acid.

The effect of high viscosity on the collapse-like chaotic and regular periodic oscillations of a harmonically excited gas bubble.

Variation in performance at different positions of an ultrasonic VialTweeter--A study based on various physical and chemical activities.

Lithium niobate ultrasonic transducer design for Enhanced Oil Recovery.

Sonochemical transformation of thymidine: A mass spectrometric study.

Ultrasound-assisted HCl-NaCl leaching of lead-rich and antimony-rich oxidizing slag.

Sonochemistry: An efficient alternative to the synthesis of 3-selanylindoles using CuI as catalyst.

In situ photo sonosynthesis and characterize nonmetal/metal dual doped honeycomb-like ZnO nanocomposites on wool fabric.

A review on sonoelectrochemical technology as an upcoming alternative for pollutant degradation.

Ultrasonic coal washing to leach alkali elements from coals.

Ultrasound assisted lipase catalyzed synthesis of cinnamyl acetate via transesterification reaction in a solvent free medium.

Sono-bromination of aromatic compounds based on the ultrasonic advanced oxidation processes.

Rapid sonochemical synthesis of novel PbSe-graphene-TiO2 composite sonocatalysts with enhanced on decolorization performance and generation of ROS.

Hysteresis of inertial cavitation activity induced by fluctuating bubble size distribution.

Conversion of carbon dioxide to resorcylic acid under ultrasonication by Kolbe-Schmitt reaction.

Shelf life, physicochemical, microbiological and antioxidant properties of purple cactus pear (Opuntia ficus indica) juice after thermoultrasound treatment.

Microwave-ultrasound assisted synthesis of ß-FeOOH and its catalytic property in a photo-Fenton-like process.

Effect of ultrasonic cavitation on the diffusivity of a point defect in the passive film on formed Nb in 0.5 M HCl solution.

The effect of ultrasonic processing on solidification microstructure and heat transfer in stainless steel melt.

Effect of ultrasound-assisted freezing on the physico-chemical properties and volatile compounds of red radish.

Designing and characterizing a multi-stepped ultrasonic horn for enhanced sonochemical performance.

Rheological and kinetic study of the ultrasonic degradation of locust bean gum in aqueous saline and salt-free solutions.

The comparison of removing plug by ultrasonic wave, chemical deplugging agent and ultrasound-chemical combination deplugging for near-well ultrasonic processing technology.

Sonocatalysis of a sulfa drug using neodymium-doped lead selenide nanoparticles.

A comparative fluid flow characterisation in a low frequency/high power sonoreactor and mechanical stirred vessel.

Effect of ultrasonic cavitation erosion on corrosion behavior of high-velocity oxygen-fuel (HVOF) sprayed near-nanostructured WC-10Co-4Cr coating.

Sonocatalytic performance of Er-doped ZnO for degradation of a textile dye.

Controlled morphology and size of curcumin using ultrasound in supercritical CO2 antisolvent.

A systematic study on the use of ultrasound energy for the synthesis of nickel-metal organic framework compounds.

A simple sonochemical method for fabricating poly(methyl methacrylate)/stearic acid phase change energy storage nanocapsules.

Ultrasound-promoted one-pot three component synthesis of tetrazoles catalyzed by zinc sulfide nanoparticles as a recyclable heterogeneous catalyst.

Sonochemical synthesis of a nano-structured zinc(II) amidic pillar metal-organic framework.

Ultrasonic-accelerated rapid protocol for the improved synthesis of pyrazoles.

Focused ultrasound solid-liquid extraction for the determination of organic biomarkers in beachrocks.

Mapping of cavitational activity in a pilot plant dyeing equipment.

Optimization of ultrasound-assisted extraction of anthocyanins from haskap berries (Lonicera caerulea L.) using Response Surface Methodology.

Simulation of thermal ablation by high-intensity focused ultrasound with temperature-dependent properties.

Direct and indirect sonication affect differently the microstructure and the morphology of ZnO nanoparticles: Optical behavior and its antibacterial activity.

MnO2/CeO2 for catalytic ultrasonic decolorization of methyl orange: Process parameters and mechanisms.

Depolymerization using sonochemical reactors: A critical review.

Dehydration kinetics of salmon and trout fillets using ultrasonic vacuum drying as a novel technique.

Ultrasonic-assisted synthesis and structural characterization of two new nano-structured Hg(II) coordination polymers.

Effect of ultrasound on the extraction of total anthocyanins from Purple Majesty potato.

Effects of ultrasonic treatment on zeolite NaA synthesized from by-product silica.

Introduction to this special edition of ultrasonics sonochemistry: 'The 1st Yangtze International Summit of Minimally-invasive and Noninvasive Medicine: Clinical Applications of HIFU (high-intensity focused ultrasound)'.

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Ultrasound Guided High Intensity Focused Ultrasound for malignant tumors: The Spanish experience of survival advantage in stage III and IV pancreatic cancer.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Vidal-Jove, Joan Perich, Eloi Del Castillo, Manuel Alvarez
Description	Author Affiliation: Vidal-Jove J ( Surgical Oncology HIFU Unit, Hospital Universitari Mutua Terrassa (HUMT), Pl. Dr. Robert, 5, 08221 Terrassa, Barcelona, Spain. Electronic address: http://www.mutuaterrassa.cat.); Perich E ( Surgical Oncology HIFU Unit, Hospital Universitari Mutua Terrassa (HUMT), Pl. Dr. Robert, 5, 08221 Terrassa, Barcelona, Spain.); del Castillo MA ( Medical Direction Departments, Hospital Universitari Mutua Terrassa (HUMT), Pl. Dr. Robert, 5, 08221 Terrassa, Barcelona, Spain.)
Abstract	UNLABELLED: We described the experience of the HIFU Onco Unit of Hospital University Mutua Terrassa (Barcelona, Spain) treating malignant tumors, focusing on results of unresectable pancreatic tumors treated with Ultrasound Guided High Intensity Focused Ultrasound (USgHIFU) hyperthermia ablation in combination with adjuvant chemotherapy. MATERIALS AND METHODS: From February 2008 to December 2013, we treated 140 malignant cases. Of those, 48 cases of unresectable pancreatic tumors were treated from March 2010 to December 2013, and the first 43 were included in the analysis. All the 43 cases (29 cases of stage III and 14 cases of stage IV) were treated with systemic chemotherapy. Clinical responses (thermical ablation achieved) were measured by image techniques, and complications were also recorded and analyzed. RESULTS: The majority of the 140 cases treated at our HIFU center were pancreatic and liver tumors, among which 43 cases of pancreatic tumors were analyzed. Clinical responses (ablation obtained) were observed in 82% of the cases, and the responses lasted at 8 weeks post-procedure. We obtained 11 complete responses (25%) at the end of the combined treatment, nine from stage III patients and two from stage IV patients. Major complications included severe pancreatitis with GI bleeding (1), and skin burning of grade III that required plastic surgery (2). The median survival was 13 months (6 months-2.7 years). No deaths were registered during the course of the treatment. CONCLUSIONS: HIFU is a potentially effective and safe modality for the treatment of malignant tumors. HIFU proves to have a survival advantage in treating unresectable pancreatic cancer.
File Format	HTM / HTML
ISSN	13504177
Volume Number	27
e-ISSN	18732828
Journal	Ultrasonics Sonochemistry
Language	English
Publisher	Elsevier
Publisher Date	2015-11-01
Publisher Place	Netherlands
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Diagnostic Imaging High-intensity Focused Ultrasound Ablation Kaplan-meier Estimate Pancreatic Neoplasms Pathology Surgery Adult Aged Humans Middle Aged Neoplasm Staging Journal Article
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Environmental Chemistry Acoustics and Ultrasonics Radiology, Nuclear Medicine and Imaging Chemical Engineering Inorganic Chemistry

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