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Coagulation profile, haematological and biochemical changes in kids naturally infected with peste des petits ruminants.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Sahinduran, Sima Albay, Metin Koray Sezer, Kenan Ozmen, Ozlem Mamak, Nuri Haligur, Mehmet Karakurum, Cagri Yildiz, Ramazan
Spatial Coverage	Turkey
Description	Country affiliation: Turkey Author Affiliation: Sahinduran S ( Department of Internal Medicine, Faculty of Veterinary Medicine, University of Mehmet, Akif Ersoy, Burdur, Turkey. sahinduran@mehmetakif.edu.tr)
Abstract	The aim of this study was to examine the coagulation profile in peste des petits ruminant (PPR) in kids. Five kids from a group of 150 animals (72 goats and 78 kids) were brought to the Veterinary Medical Teaching Hospital from a farm in Burdur province (Turkey) with nasal and ocular discharges and diarrhea. Fifteen goats and 41 kids had died due to diarrhea and three kids were presented to the Department of Pathology for diagnosis. Blood samples were taken from 12 ill animals (infected group) for haematological and biochemical analysis. In addition, five healthy kids were examined from another healthy flock (control group). Leukocyte and lymphocyte numbers of infected group showed significant declinations in comparison to control group (≤0.001). Haemorrhages in all organs of digestive system and small haemorrhagic areas in liver were caused to decrease in erythrocyte and haematocrit values (p ≤ 0.001) in infected group. Concentrations of blood urea nitrogen (BUN) (p ≤ 0.01) and creatinine (p ≤ 0.001) in infected group were significantly higher than control group. Compared to control group, significant increases were determined in serum concentrations of alkaline phosphatase (ALP) (p ≤ 0.01), aspartate aminotransferase (AST) (p ≤ 0.001) and alanine aminotransferase (ALT) (p ≤ 0.001) in the infected group. No significant differences were observed between the infected and control groups for serum gamma glutamyl-transferase (GGT) concentration value. In our study, thrombocytopenia (p ≤ 0.001) together with prolonged activated partial thromboplastin time (APTT; p ≤ 0.01) and prothrombin time (PT; p ≤ 0.001) may show that disseminated intravascular coagulopathy which can occur in kids with PPR.
File Format	HTM / HTML
ISSN	00494747
Issue Number	3
Volume Number	44
e-ISSN	15737438
Journal	Tropical Animal Health and Production
Language	English
Publisher	Springer
Publisher Date	2012-03-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Veterinary Medicine Discipline Tropical Medicine Blood Coagulation Disseminated Intravascular Coagulation Veterinary Goat Diseases Blood Peste-des-petits-ruminants Peste-des-petits-ruminants Virus Physiology Thrombocytopenia Animals Blood Chemical Analysis Enzyme-linked Immunosorbent Assay Pathology Goats Partial Thromboplastin Time Prothrombin Time Turkey Journal Article
Content Type	Text
Resource Type	Article
Subject	Animal Science and Zoology Food Animals

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Coagulation profile, haematological and biochemical changes in kids naturally infected with peste des petits ruminants

Detection of peste des petits ruminants virus in formalin-fixed tissues.

The detection of antibody against peste des petits ruminants virus in sheep, goats, cattle and buffaloes.

Prevalence of antibodies to peste des petits ruminants virus before and during outbreaks of the disease in Awash Fentale district, Afar, Ethiopia.

Current situation of Peste des petits ruminants (PPR) in the Sudan.

Peste des petits ruminants virus (PPRV) infection; its association with species, seasonal variations and geography.

Persistent detection of peste de petits ruminants antigen in the faeces of recovered goats.

First serological investigation of peste-des-petits-ruminants and Rift Valley fever in Tunisia.

Prevalence, distribution, and host range of Peste des petits ruminants virus, Turkey.

Coagulation profile, haematological and biochemical changes in kids naturally infected with peste des petits ruminants.

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Coagulation profile, haematological and biochemical changes in kids naturally infected with peste des petits ruminants

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Coagulation profile, haematological and biochemical changes in kids naturally infected with peste des petits ruminants.