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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Özgür, A. Arslanoglu, S. Etit, D. Demiray, U. Önal, H. K. |
| Description | Country affiliation: Turkey Author Affiliation: Özgür A ( Department of Otorhinolaryngology, Izmir Atatürk Training and Research Hospital, Turkey.) |
| Abstract | OBJECTIVE: To evaluate symptom scores and nasal smear cytology findings in seasonal allergic rhinitis patients, before and after treatment. METHODS: Twenty-nine consecutive adult patients with seasonal allergic rhinitis were evaluated prospectively. They received mometasone furoate nasal spray and cetirizine for 21 days. Nasal and ocular symptom scores were recorded before and after treatment. Nasal cytology was also assessed as a means of determining treatment. RESULTS: The combined use of an intranasal corticosteroid and an oral antihistamine caused a significant improvement in nasal and ocular symptom scores. Cytological evaluation revealed significant reduction in nasal eosinophil, neutrophil and goblet cell counts after three weeks' treatment. CONCLUSION: Symptom scoring systems are widely used for the evaluation of drug efficacy in allergic rhinitis treatment. When investigating the disease and evaluating treatment efficacy, objective as well as subjective methods are needed. Nasal cytological assessment is a simple, objective method which provides valuable information about the nasal mucosa. |
| File Format | HTM / HTML |
| ISSN | 00222151 |
| Issue Number | 10 |
| Volume Number | 125 |
| e-ISSN | 17485460 |
| Journal | The Journal of Laryngology & Otology |
| Language | English |
| Publisher | Cambridge University Press |
| Publisher Date | 2011-10-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Otolaryngology Anti-allergic Agents Therapeutic Use Cetirizine Nasal Mucosa Cytology Pregnadienediols Rhinitis, Allergic, Seasonal Drug Therapy Administration, Intranasal Adult Aged Administration & Dosage Drug Therapy, Combination Female Granulocytes Humans Male Middle Aged Mometasone Furoate Nasal Obstruction Prospective Studies Pathology Physiopathology Treatment Outcome Young Adult Journal Article |
| Content Type | Text |
| Resource Type | Article |
| Subject | Otorhinolaryngology |
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