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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Kataria, Manisha Narang, Subina Chawla, Deepak Sood, Sunandan Gupta, Parul Chawla |
| Description | Country affiliation: India Author Affiliation: Kataria M ( Department of Ophthalmology, Government Medical College and Hospital, Sector 32, Chandigarh, India.) |
| Abstract | OBJECTIVE: To evaluate efficacy of oral dextrose, in addition to topical anesthesia in providing pain relief during laser ablation therapy of retinopathy of prematurity (ROP). METHODS: In this randomized controlled trial, neonates with type 1 ROP undergoing laser ablation of peripheral retina were randomized to receive or not to receive 2 ml of 25 % dextrose orally just before the laser therapy. In both the groups, topical anesthesia was provided by instilling paracaine eye drops twice at 10 min interval just before the laser treatment. Main outcome was Premature Infant Pain Profile (PIPP) recorded before and 30 s after starting the laser treatment. RESULTS: Birth weight, gestation, stage and extent of ROP and other baseline variables were comparable among neonates randomized to dextrose (n = 12) or control (n = 12) groups. Both groups required comparable number of laser spots. PIPP scores was comparable in neonates randomized to dextrose or control groups and indicated significant amount of pain felt during laser ablation despite local anesthesia with or without oral dextrose. CONCLUSIONS: Single dose of oral dextrose did not significantly reduce pain during laser treatment in premature neonates. Further studies with multiple doses of dextrose and its combination with other non-pharmacological (e.g., behavioral, physical) interventions may be needed. |
| File Format | HTM / HTML |
| ISSN | 00195456 |
| Issue Number | 8 |
| Volume Number | 82 |
| e-ISSN | 09737693 |
| Journal | The Indian Journal of Pediatrics |
| Language | English |
| Publisher | Springer |
| Publisher Date | 2015-08-01 |
| Publisher Place | India |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Pediatrics Anesthetics, Local Administration & Dosage Glucose Laser Therapy Methods Pain Drug Therapy Retinopathy Of Prematurity Surgery Administration, Oral Therapeutic Use Humans Infant Infant, Newborn Infant, Premature Adverse Effects Pain Management Pain Measurement Journal Article Randomized Controlled Trial |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pediatrics, Perinatology and Child Health |
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