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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Uskul, Bahadir T. Turker, Hatice Kant, Aydin Partal, Mualla |
| Description | Country affiliation: Turkey Author Affiliation: Uskul BT ( Chest Diseases Department, Sureyyapasa Teaching and Research Hospital for Chest Diseases and Thoracic Surgery, Istanbul, Turkey. tbuskul@yahoo.com) |
| Abstract | OBJECTIVE: To evaluate the diagnostic contribution and utility of bacteriologic surveys using bronchoscopic washing and gastric lavage in cases of radiologically suspected tuberculosis with no detectable acid-fast bacilli (AFB) in the sputum. MATERIAL AND METHODS: This prospective study performed bronchoscopic lavage following gastric washing in suspected pulmonary tuberculosis patients. The presence of AFB was determined via direct microscopy and materials were cultured in Löwenstein-Jensen medium. RESULTS: Thirty-eight consecutive patients were enrolled in the study (30 males and 8 females; mean age, 33.8 +/- 10.9 years). Three patients could not give sputum. In 23 of 35 cases (66%), sputum cultures (SC) were positive. In 17 cases (49%), gastric lavage cultures (GLC) were positive. Eighteen cases (55%) had positive bronchoscopic washing cultures (BWC). No statistically significant difference was observed when SC positivity was compared to GLC and BWC, and no difference was observed when the GLC results were compared with BWC. Tuberculosis was confirmed in 30 of 38 (79%) patients when SC and GLC were evaluated together, in 33 of 38 patients (87%) when SC and BWC were evaluated together, and in 36 of 38 (95%) when SC, GLC, and BWC were evaluated together (P = 0.016, P = 0.002, and P = 0.0001, respectively). The increase in positive cultures was statistically significant when gastric lavage was evaluated together with bronchoscopic washing (P = 0.004). CONCLUSION: Adding gastric lavage and bronchial washing to sputum culture could increase culture positivity for M tuberculosis bacilli in suspected pulmonary tuberculosis patients with AFB-negative sputum smears. |
| File Format | HTM / HTML |
| ISSN | 00384348 |
| Issue Number | 2 |
| Volume Number | 102 |
| e-ISSN | 15418243 |
| Journal | Southern Medical Journal |
| Language | English |
| Publisher | Lippincott Williams & Wilkins (for the Southern Medical Association) |
| Publisher Date | 2009-02-01 |
| Publisher Place | United States |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Medicine Bronchoalveolar Lavage Bronchoscopy Methods Gastric Lavage Tuberculosis, Pulmonary Diagnosis Adult Chi-square Distribution Female Humans Male Prospective Studies Sputum Microbiology Comparative Study Journal Article |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine |
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