NDLI: Aliskiren-induced QT interval prolongation.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Peitz, Gregory J. Malesker, Mark A. Sojka, S. George
Description	Country affiliation: United States Author Affiliation: Peitz GJ ( Pharmacy Department, Sanford USD Medical Center, Sioux Falls, SD 57117-5039, USA. peitzg@sanfordhealth.org)
Abstract	Aliskiren gained FDA approval for the treatment of hypertension in 2007. It is the first approved pharmaceutical to manage hypertension by direct renin inhibition. With the introduction of novel drugs and mechanisms of action comes the challenge of monitoring for new unreported adverse events. The side effect profile for aliskiren has not yet been fully described. We describe the first apparent report of aliskiren-induced QT prolongation resulting in torsades de pointes.
File Format	HTM / HTML
ISSN	00384348
Issue Number	4
Volume Number	102
e-ISSN	15418243
Journal	Southern Medical Journal
Language	English
Publisher	Lippincott Williams & Wilkins (for the Southern Medical Association)
Publisher Date	2009-04-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Medicine Amides Adverse Effects Antihypertensive Agents Fumarates Long Qt Syndrome Chemically Induced Aged Anti-arrhythmia Agents Female Humans Sotalol Case Reports Journal Article
Content Type	Text
Resource Type	Case study Article
Subject	Medicine

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Aliskiren-induced QT interval prolongation.