NDLI: Native adipose stromal cells egress from adipose tissue in vivo: evidence during lymph node activation.

Please wait, while we are loading the content...

Natriuretic peptide receptor A signaling regulates stem cell recruitment and angiogenesis: a model to study linkage between inflammation and tumorigenesis.

Endogenous distal airway progenitor cells, lung mechanics, and disproportionate lobar growth following long-term postpneumonectomy in mice.

Promotion of osteoblast differentiation in mesenchymal cells through Cbl-mediated control of STAT5 activity.

Periodontal ligament stem cells regulate B lymphocyte function via programmed cell death protein 1.

IFN-Î³ and TNF- synergistically induce mesenchymal stem cell impairment and tumorigenesis via NFκB signaling.

Disease-causing mitochondrial heteroplasmy segregated within induced pluripotent stem cell clones derived from a patient with MELAS.

Corneal endothelial cell fate is maintained by LGR5 through the regulation of hedgehog and Wnt pathway.

Essential role of Sox2 for the establishment and maintenance of the germ cell line.

Concise review: hematopoietic stem cell transplantation: targeting the thymus.

Repression of Zeb1 and hypoxia cause sequential mesenchymal-to-epithelial transition and induction of aid, Oct4, and Dnmt1, leading to immortalization and multipotential reprogramming of fibroblasts in spheres.

Uterine vasculature remodeling in human pregnancy involves functional macrochimerism by endothelial colony forming cells of fetal origin.

Concise review: erythroid versus myeloid lineage commitment: regulating the master regulators.

Entinostat prevents leukemia maintenance in a collaborating oncogene-dependent model of cytogenetically normal acute myeloid leukemia.

FoxG1 interacts with Bmi1 to regulate self-renewal and tumorigenicity of medulloblastoma stem cells.

p130Cas alters the differentiation potential of mammary luminal progenitors by deregulating c-Kit activity.

Concise review: pursuing self-renewal and pluripotency with the stem cell factor Nanog.

A tale of two sisters.

Year: 2013 Volume: 31 Issue: 6

Year: 2013 Volume: 31 Issue: 5

Year: 2013 Volume: 31 Issue: 4

Year: 2013 Volume: 31 Issue: 3

Year: 2013 Volume: 31 Issue: 2

Year: 2013 Volume: 31 Issue: 1

Year: 2012 Volume: 30

Year: 2011 Volume: 29

Year: 2010 Volume: 28

Year: 2009 Volume: 27

Year: 2008 Volume: 26

Year: 2007 Volume: 25

Native adipose stromal cells egress from adipose tissue in vivo: evidence during lymph node activation.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Gil-Ortega, Marta Garidou, Lucile Barreau, Corinne Maumus, Marie Breasson, Ludovic Tavernier, Geneviève García-Prieto, Concha F. Bouloumié, Anne Casteilla, Louis Sengenès, Coralie
Description	Country affiliation: France Author Affiliation: Gil-Ortega M ( CNRS, Université Toulouse III, Toulouse, France.)
Abstract	Adipose tissue (AT) has become accepted as a source of multipotent progenitor cells, the adipose stromal cells (ASCs). In this regard, considerable work has been performed to harvest and characterize this cell population as well as to investigate the mechanisms by which transplanted ASCs mediate tissue regeneration. In contrast the endogenous release of native ASCs by AT has been poorly investigated. In this work, we show that native ASCs egress from murine AT. Indeed, we demonstrated that the release of native ASCs from AT can be evidenced both using an ex vivo perfusion model that we set up and in vivo. Such a mobilization process is controlled by CXCR4 chemokine receptor. In addition, once mobilized from AT, circulating ASCs were found to navigate through lymph fluid and to home into lymph nodes (LN). Therefore, we demonstrated that, during the LN activation, the fat depot encapsulating the activated LN releases native ASCs, which in turn invade the activated LN. Moreover, the ASCs invading the LN were visualized in close physical interaction with podoplanin and ER-TR7 positive structures corresponding to the stromal network composing the LN. This dynamic was impaired with CXCR4 neutralizing antibody. Taken together, these data provide robust evidences that native ASCs can traffic in vivo and that AT might provide stromal cells to activated LNs.
File Format	HTM / HTML
ISSN	10665099
Issue Number	7
Volume Number	31
e-ISSN	15494918
Journal	STEM CELLS
Language	English
Publisher	Wiley
Publisher Date	2013-07-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Cell Biology Discipline Embryology Adipose Tissue Cytology Lymph Nodes Mesenchymal Stromal Cells Metabolism Animals Cell Differentiation Physiology Cell Growth Processes Chemokine Cxcl12 Immunophenotyping Male Mice Mice, Inbred C57bl Receptors, Cxcr4 Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Cell Biology Developmental Biology Medicine Molecular Medicine

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

The CXCL12 (SDF-1)/CXCR4 axis is essential for the development of renal vasculature.

Pharmacologically antagonizing the CXCR4-CXCL12 chemokine pathway with AMD3100 inhibits sunlight-induced skin cancer.

Umbilical cord blood-derived mesenchymal stem cells inhibit, but adipose tissue-derived mesenchymal stem cells promote, glioblastoma multiforme proliferation.

Dendritic cells distinguish individual chemokine signals through CCR7 and CXCR4.

Lymph Node Stromal Fiber ER-TR7 Modulates CD4+ T Cell Lymph Node Trafficking and Transplant Tolerance.

Generation of lymph node-fat pad chimeras for the study of lymph node stromal cell origin.

Ex Vivo Induced Regulatory Human/Murine Mesenchymal Stem Cells as Immune Modulators.

CCAAT/enhancer-binding protein ß expressed by bone marrow mesenchymal stromal cells regulates early B-cell lymphopoiesis.

The spleen recruits endothelial progenitor cell via SDF-1/CXCR4 axis in mice.

Native adipose stromal cells egress from adipose tissue in vivo: evidence during lymph node activation.

Similar Documents

The CXCL12 (SDF-1)/CXCR4 axis is essential for the development of renal vasculature.

Pharmacologically antagonizing the CXCR4-CXCL12 chemokine pathway with AMD3100 inhibits sunlight-induced skin cancer.

Umbilical cord blood-derived mesenchymal stem cells inhibit, but adipose tissue-derived mesenchymal stem cells promote, glioblastoma multiforme proliferation.

Dendritic cells distinguish individual chemokine signals through CCR7 and CXCR4.

Lymph Node Stromal Fiber ER-TR7 Modulates CD4+ T Cell Lymph Node Trafficking and Transplant Tolerance.

Generation of lymph node-fat pad chimeras for the study of lymph node stromal cell origin.

Ex Vivo Induced Regulatory Human/Murine Mesenchymal Stem Cells as Immune Modulators.

CCAAT/enhancer-binding protein ß expressed by bone marrow mesenchymal stromal cells regulates early B-cell lymphopoiesis.

The spleen recruits endothelial progenitor cell via SDF-1/CXCR4 axis in mice.

Native adipose stromal cells egress from adipose tissue in vivo: evidence during lymph node activation.