NDLI: Non-smoking-related chronic obstructive pulmonary disease: a neglected entity?

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Non-smoking-related chronic obstructive pulmonary disease: a neglected entity?

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Non-smoking-related chronic obstructive pulmonary disease: a neglected entity?

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Zeng, Guangqiao Sun, Baoqing Zhong, Nanshan
Description	Country affiliation: China Author Affiliation: Zeng G ( State Key Laboratory of Respiratory Disease, First Affiliated Hospital, Guangzhou Medical College, Guangzhou, China.)
Abstract	Chronic obstructive pulmonary disease (COPD) is an increasing cause of morbidity and mortality worldwide, and it has been strongly correlated to tobacco smoking. While a number of studies have concentrated on smokers only, recent published data demonstrate that at least one fourth of patients with COPD are non-smokers, and that the burden of COPD in non-smokers is also higher than previously believed. Risk factors of COPD in non-smokers may include genetic factors, long-standing asthma, outdoor air pollution (from traffic and other sources), environmental smoke exposure (ETS), biomass smoke, occupational exposure, diet, recurrent respiratory infection in early childhood, tuberculosis and so on. In Asian region, indoor/outdoor air pollution and poor socioeconomic status may play important roles in the pathogenesis of non-smoking-related COPD. The prevalence of COPD among never smokers varies widely across nations. Such a variation may arise from several aspects, including study design, definition of COPD, diagnostic criteria, age and gender distribution of the studied population, local risk factors and socioeconomic status. More investigations and efforts are required to elucidate the involved factors and their shared contributions to non-smoking-related COPD so as to achieve better estimation and reduction of the burden of this neglected entity worldwide.
File Format	HTM / HTML
ISSN	13237799
Issue Number	6
Volume Number	17
e-ISSN	14401843
Journal	Respirology
Language	English
Publisher	Wiley
Publisher Date	2012-08-01
Publisher Place	Australia
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Pulmonary Medicine Neglected Diseases Epidemiology Pulmonary Disease, Chronic Obstructive Air Pollution Adverse Effects Asthma Genetics Female Humans Male Occupational Exposure Prevalence Etiology Risk Factors Smoke Vehicle Emissions Journal Article Review
Content Type	Text
Resource Type	Article
Subject	Pulmonary and Respiratory Medicine

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