NDLI: Delay of puberty and reproductive performance in male dogs following the implantation of 4.7 and 9.4 mg GnRH-agonist deslorelin at an early pre-pubertal age.

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Stimulation of mating-induced uterine contractions in the bitch and their modification and enhancement of fertility by prostatic fluid.

Research challenges in endocrine aspects of canine ovarian cycles.

Endocrine and molecular control of luteal and placental function in dogs: a review.

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Leptin and leptin receptor gene expression in the canine corpus luteum during diestrus, pregnancy and after aglepristone-induced luteolysis.

Ovulation compensatory function after unilateral ovariectomy in dogs.

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In vitro survival of follicles collected from domestic cats' ovaries at different stages of oestrous cycle and cultured with IGF-1.

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Scriptaid and 5-aza-2'deoxycytidine enhanced expression of pluripotent genes and in vitro developmental competence in interspecies black-footed cat cloned embryos.

Cryopreservation of canine embryos and resulting pregnancies.

Ex vivo recovery of preimplantatory embryos in bitches.

Capabilities and challenges of examination of gene expression for quality assessment of domestic cat embryos.

Source of protein supplementation during in vitro culture does not affect the quality of resulting blastocysts in the domestic cat.

Embryo retrieval after hormonal treatment to control ovarian function and non-surgical artificial insemination in African lions (Panthera leo).

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Progesterone (PR), oestrogen (ER- and ER-ß) and oxytocin (OTR) gene expression in the oviduct and uterus of pregnant and non-pregnant bitches.

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Evaluation of sperm DNA peroxidation in fertile and subfertile dogs.

Use of fluorescent stainings and flow cytometry for canine semen assessment.

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Unilateral orchidectomy in mature cats is not followed by compensatory hypertrophy.

Validation of a model to develop a symptom index for benign prostatic hyperplasia in dogs.

Effect of natural photoperiod on epididymal sperm quality and testosterone serum concentration in domestic cat (Felis silvestris catus).

Effect of refractoriness to long photoperiod on sperm production and quality in tomcats.

B-mode and contrast-enhanced ultrasonographic findings in canine prostatic disorders.

Testicular steroids, prolactin, relaxin and prostate gland markers in peripheral blood and seminal plasma of normal dogs and dogs with prostatic hyperplasia.

Spermatogenic function in cats.

Seasonal aspects of reproductive physiology in captive male maned wolves (Chrysocyon brachyurus, Illiger 1815).

Molecular markers of spermatogonial stem cells in the domestic cat.

Cryosurvival of ex situ and in situ feline oocytes.

Customizing semen preservation protocols for individual dogs and individual species: sperm preservation beyond the state of the art.

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Effects of cooling time on membrane integrity and motility of frozen-thawed canine spermatozoa using two different commercial egg yolk-based extenders at two different cooldown equilibration times.

Effect of storage media and storage time on histological and ultrastructural changes in cat epididymal cells.

Comparative fertility of freshly collected vs frozen-thawed semen with laparoscopic oviductal artificial insemination in domestic cats.

Intravaginal artificial insemination in bitches using frozen/thawed semen after dilution in powdered coconut water (ACP-106c).

Comparison of two different extenders for cryopreservation of epididymal dog sperm.

Vitrification of domestic cat oocytes--effect on viability and integrity of subcellular structures.

Preservation of primordial follicles from lions by slow freezing and xenotransplantation of ovarian cortex into an immunodeficient mouse.

Birth of kittens after the transfer of frozen-thawed embryos produced by intracytoplasmic sperm injection with spermatozoa collected from cryopreserved testicular tissue.

Application of genomic and molecular methods to fundamental questions in canine and feline reproductive health.

Progesterone receptor isoforms in the mammary gland of cats and dogs.

Diseases of the canine uterus.

Clinical and molecular characteristics of pyometra in female dogs.

Food intake and nutrition during pregnancy, lactation and weaning in the dam and offspring.

Effect of simulated stages of the canine oestrous cycle on Escherichia coli binding to canine endometrium.

Lactate in bitches with pyometra.

Cytokines as immunological markers for systemic inflammation in dogs with pyometra.

Diagnostic value of transcervical endometrial biopsies in domestic dogs compared with full-thickness uterine sections.

Breed variations in the incidence of pyometra and mammary tumours in Swedish dogs.

The localization of Toll-like receptor 2 (TLR2) in the endometrium and the cervix of dogs at different stages of the oestrous cycle and with pyometra.

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Application of vaginal temperature measurement in bitches.

Canine herpesvirus during pregnancy and non-pregnant luteal phase.

Successful management of metastatic transmissible venereal tumour to skin of mammary region.

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Effects of GnRH antagonists vs agonists in domestic carnivores, a review.

AZA Wildlife Contraception Center programme for wild felids and canids.

Litter size response to oestrous induction with deslorelin (Ovuplant®) in dogs.

Semen quality and onset of sterility following administration of a 4.7-mg deslorelin implant in adult male dogs.

Results of GnRH agonist implants in oestrous induction and oestrous suppression in bitches and queens.

Clinical evaluation of deslorelin to induce oestrus, ovulation and pregnancy in the bitch.

Delay of puberty and reproductive performance in male dogs following the implantation of 4.7 and 9.4 mg GnRH-agonist deslorelin at an early pre-pubertal age.

Physiologic responses following gonadotropin-releasing hormone immunization in intact male dogs.

Generation and characterization of phage-GnRH chemical conjugates for potential use in cat and dog immunocontraception.

The symposium from 26 to 29 July 2012 at the Westin Whistler Resort, Whistler Mountain Village, British Columbia, Canada. Foreword.

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Delay of puberty and reproductive performance in male dogs following the implantation of 4.7 and 9.4 mg GnRH-agonist deslorelin at an early pre-pubertal age.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Sirivaidyapong, S. Mehl, N. S. Trigg, T. E.
Description	Country affiliation: Thailand Author Affiliation: Sirivaidyapong S ( Department of Obstetrics, Faculty of Veterinary Science, Small Animal Teaching Hospital, Chulalongkorn University, Bangkok, Thailand. s_sudson@yahoo.co.uk)
Abstract	CONTENTS: Stray dogs are a significant problem in large cities. Contraception is an important and useful solution to control the growing population of these dogs. Early-age neutering is an effective technique for canine population control; however, surgical neutering may not be possible in various situations. GnRH-agonist implantation has been successful for long-term reversible contraception in dogs. The efficacy of GnRH-agonist implantation on long-term suppression of reproductive performance was observed in male dogs. Eleven 4-month-old dogs were implanted with 4.7, 9.4 mg deslorelin or placebo. Sexual behaviour and testicular size were monitored every 2 months. Ejaculates were collected and evaluated at 8, 12, 15, 18, 24, 30, 32, 34 and 36 months of age. Dogs implanted with placebo were found to be healthy and in normal reproductive status. Most dogs (3/4) implanted with 4.7 mg deslorelin showed male sexual behaviour at age of 34 months old. From this group, two dogs had normal semen quality, while semen could not be collected from the other dog, and after castration, no sperm were obtained following epididymal flushing. One dog implanted 4.7 mg deslorelin and four dogs implanted with 9.4 mg deslorelin remained in the non-pubertal reproductive status at 30-34 months. The delay to puberty was longer in dogs implanted with higher dose of GnRH agonist. Implantation of pre-pubertal dogs with high doses of GnRH agonist will delay the onset of puberty and may be an effective strategy to reduce the number of unwanted breedings.
File Format	HTM / HTML
ISSN	09366768
Issue Number	Suppl 6
Volume Number	47
e-ISSN	14390531
Journal	Reproduction in Domestic Animals
Language	English
Publisher	Wiley
Publisher Date	2012-12-01
Publisher Place	Germany
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Reproductive Medicine Discipline Veterinary Medicine Discipline Zoology Dogs Gonadotropin-releasing Hormone Agonists Reproduction Physiology Sexual Maturation Drug Effects Triptorelin Pamoate Analogs & Derivatives Animals Contraception Methods Veterinary Contraceptive Agents, Male Administration & Dosage Pharmacology Male Testis Anatomy & Histology Journal Article
Content Type	Text
Resource Type	Article
Subject	Animal Science and Zoology Endocrinology Biotechnology

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