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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Stenberg, Arne Läckgren, Göran |
| Description | Country affiliation: Sweden Author Affiliation: Stenberg A ( Section of Urology, University Children's Hospital, S-751 85 Uppsala, Sweden. arne.stenberg@surgsci.uu.se) |
| Abstract | OBJECTIVE: Vesicoureteral reflux (VUR) can be treated with open surgery, antibiotic therapy or endoscopic injection. A goal in children is to reduce the incidence of febrile urinary tract infections (UTIs). The present long-term observational study investigated outcomes and experiences of endoscopic treatment with stabilized non-animal hyaluronic acid/dextranomer, NASHA/Dx. PATIENTS AND METHODS: Children treated with NASHA/Dx between 1993 and 1998 were sent a questionnaire by mail in 2005. Patients included in the study (n=231) had VUR grade III-V before treatment and grade 0-II afterwards. Patients completed 21 questions, with parental assistance if required. The questionnaire assessed clinical outcome, and the attitudes of both patients and their parents to their experiences of treatment with NASHA/Dx gel. Patients reporting UTI after treatment were contacted and their records analyzed. RESULTS: Questionnaires were completed by 179 eligible patients. Most (72%) received a single injection of NASHA/Dx gel, and all experienced febrile UTI before treatment. After treatment, 45 patients (25%) experienced UTI; 25 of these reported fever. Patient records and telephone interviews revealed no evidence of febrile UTI in 19 cases; febrile UTI was confirmed in six cases, an incidence of 3.4%. When asked about the worst aspect of VUR treatment, 9% indicated treatment with NASHA/Dx compared to 19% for medication and 72% for voiding cystourethrogram (VCUG); parent-rated responses were 19%, 24% and 57%, respectively. CONCLUSIONS: Endoscopic treatment with NASHA/Dx gel was associated with a low number of febrile UTIs following treatment, viewed positively and considered less bothersome than medication or VCUG. These findings support this treatment as a primary intervention for VUR. |
| File Format | HTM / HTML |
| ISSN | 14775131 |
| Issue Number | 2 |
| Journal | Journal of Pediatric Urology |
| Volume Number | 3 |
| e-ISSN | 18734898 |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2007-04-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Urology Discipline Pediatrics |
| Content Type | Text |
| Resource Type | Article |
| Subject | Urology Pediatrics, Perinatology and Child Health |
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