NDLI: Degradable borate glass polyalkenoate cements.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Shen, L. Coughlan, A. Towler, M. Hall, M.
Description	Country affiliation: United States Author Affiliation: Shen L ( Kazuo Inamori School of Engineering, Alfred University, Binns-Merrill Hall, 2 Pine Street, Alfred, NY, 14802, USA.)
Abstract	Glass polyalkenoate cements (GPCs) containing aluminum-free borate glasses having the general composition Ag2O-Na2O-CaO-SrO-ZnO-TiO2-B2O3 were evaluated in this work. An initial screening study of sixteen compositions was used to identify regions of glass formation and cement compositions with promising rheological properties. The results of the screening study were used to develop four model borate glass compositions for further study. A second round of rheological experiments was used to identify a preferred GPC formulation for each model glass composition. The model borate glasses containing higher levels of TiO2 (7.5 mol %) tended to have longer working times and shorter setting times. Dissolution behavior of the four model GPC formulations was evaluated by measuring ion release profiles as a function of time. All four GPC formulations showed evidence of incongruent dissolution behavior when considering the relative release profiles of sodium and boron, although the exact dissolution profile of the glass was presumably obscured by the polymeric cement matrix. Compression testing was undertaken to evaluate cement strength over time during immersion in water. The cements containing the borate glass with 7.5 mol % TiO2 had the highest initial compressive strength, ranging between 20 and 30 MPa. No beneficial aging effect was observed-instead, the strength of all four model GPC formulations was found to degrade with time.
File Format	HTM / HTML
ISSN	09574530
Issue Number	4
Volume Number	25
e-ISSN	15734838
Journal	Journal of Materials Science: Materials in Medicine
Language	English
Publisher	Springer
Publisher Date	2014-04-01
Publisher Place	United States
Access Restriction	Subscribed
Subject Keyword	Discipline Biomedical Engineering Glass Ionomer Cements Chemistry Absorbable Implants Borates Compressive Strength Humans Materials Testing Particle Size Powder Diffraction Rheology Silver Strontium Titanium Journal Article
Content Type	Text
Resource Type	Article
Subject	Biomaterials Biophysics Bioengineering Biomedical Engineering

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