NDLI: Fabrication of strongly attached hydroxyapatite coating on titanium by hydrothermal treatment of $Ti–Zn–PO_{4}$ coated titanium in $CaCl

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Valanezhad, Alireza Tsuru, Kanji Ishikawa, Kunio
Description	Author Affiliation: Valanezhad A ( Department of Biomaterials, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan, vala@nagasaki-u.ac.jp.)
Abstract	Hydroxyapatite (HAp) coating was formed on zinc phosphate $(Ti–Zn–PO_{4})$ coated Ti plates by hydrothermal treatment in $CaCl_{2}$ solution at 200 °C for 12 h. Uniform surface coverage of the fabricated HAp coating was obtained by this method. SEM-EDX analysis of the adhesion test area showed that the presence of fractures only occurred in HAp crystals. On the other words cohesive fracture was seen in HAp coating layer formed on the $Ti–Zn–PO_{4}.$ The measured strength was around 42.3 ± 17 MPa. Rat bone marrow (RBM) mesenchymal stem cells were cultured and differentiation-induced on each sample (Ti plate, $Ti–Zn–PO_{4}$ coated and HAp coated), and cell calcification properties were examined. Apparent differences in morphology and extension of the RBM cells were obtained, while the $Ti–Zn–PO_{4}$ coated samples showed the highest cell number among all samples. After differentiation-induction, HAp coated samples showed the highest amount of alkaline phosphatase activity, and the highest level of cell calcification. Therefore, the hard tissue compatibility of Ti is improved by hydrothermally HAp coating of samples.
File Format	HTM / HTML
ISSN	09574530
Issue Number	7
Volume Number	26
e-ISSN	15734838
Journal	Journal of Materials Science: Materials in Medicine
Language	English
Publisher	Springer
Publisher Date	2015-07-01
Publisher Place	United States
Access Restriction	Subscribed
Subject Keyword	Discipline Biomedical Engineering Calcium Chloride Chemistry Coated Materials, Biocompatible Durapatite Phosphates Titanium Zinc Compounds Alkaline Phosphatase Metabolism Animals Bone Marrow Cells Cytology Enzymology Cells, Cultured Microscopy, Electron, Scanning Osteocalcin Rats Solutions X-ray Diffraction Journal Article
Content Type	Text
Resource Type	Article
Subject	Biomaterials Biophysics Bioengineering Biomedical Engineering

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