NDLI: Administration of beta2-adrenergic agonists during the peri-implantation period does not improve implantation or pregnancy rates in intracytoplasmic sperm injection (ICSI) cycles.

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Involvement of interleukin-1 and the interleukin-1 receptor antagonist in in vitro embryo development among women undergoing in vitro fertilization-embryo transfer.

Human oocyte maturity in vivo determines the outcome of blastocyst development in vitro.

Administration of beta2-adrenergic agonists during the peri-implantation period does not improve implantation or pregnancy rates in intracytoplasmic sperm injection (ICSI) cycles.

Effects of vaginal progesterone administration starting on the day of oocyte retrieval on pregnancy rates.

Early hormonal markers of pregnancy outcome after in vitro fertilization and embryo transfer.

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Administration of beta2-adrenergic agonists during the peri-implantation period does not improve implantation or pregnancy rates in intracytoplasmic sperm injection (ICSI) cycles.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Pinheiro, Osni L. Cavagna, Mario Baruffi, Ricardo L. R. Mauri, Ana L. Petersen, Claudia Franco, José G.
Description	Country affiliation: Brazil Author Affiliation: Pinheiro OL ( Department of Gynecology and Obstetrics, Faculty of Medicine of Botucatu (UNESP), Botucatu, Brazil.)
Abstract	PURPOSE: The objective of the present investigation was to determine implantation and pregnancy rates in patients undergoing ICSI and treated with beta2-adrenergic agonists, considering the uterine-relaxing action of these agents. METHODS: A total of 225 women undergoing ICSI at the Center for Human Reproduction, 'Sinhá Junqueira' Maternity Foundation, entered the study. Patient participation in each group was random, by drawing lots, using a randomization table previously elaborated for the study (2:2:1). The group I (90 women) received 10 mg of terbutaline daily for 15 days starting on the day of oocyte retrieval; group II (90 women) received 20 mg of ritodrine daily during the same period of time as group I; group III (45 patients) received no treatment and was used as control. The evaluation was interrupted in 3 patients of group I and in 30 patients of group II because of a high incidence of side effects. RESULTS: Pregnancy, implantation, and miscarriage rates were not significantly different (p > 0.05) between the three groups: 29.88%, 13.25%, and 26.9% for group I; 33.33%, 17.5%, and 10.0% for group II; 28.88%, 15.07%, and 15.38% for group III, respectively. CONCLUSIONS: The results of this study do not support the routine use of beta2-adrenergic agonists during the peri-implantation period in assisted reproductive technology cycles.
File Format	HTM / HTML
ISSN	10580468
e-ISSN	15737330
Journal	Journal of Assisted Reproduction and Genetics
Issue Number	12
Volume Number	20
Language	English
Publisher	Springer
Publisher Date	2003-12-01
Publisher Place	Netherlands
Access Restriction	Open
Subject Keyword	Discipline Reproductive Medicine Discipline Genectics Adrenergic Beta-2 Receptor Agonists Adrenergic Beta-agonists Pharmacology Embryo Implantation Drug Effects Pregnancy Outcome Sperm Injections, Intracytoplasmic Terbutaline Pregnancy Clinical Trial Randomized Controlled Trial
Content Type	Text
Resource Type	Article
Subject	Genetics Developmental Biology Reproductive Medicine Genetics (clinical) Obstetrics and Gynecology

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Administration of β 2-Adrenergic Agonists During the Peri-Implantation Period Does Not Improve Implantation or Pregnancy Rates in Intracytoplasmic Sperm Injection (ICSI) Cycles

Low-dose aspirin does not increase implantation rates in patients undergoing intracytoplasmic sperm injection: a prospective randomized study.

Pronuclear and morphological features as a cumulative score to select embryos in ICSI (intracytoplasmic sperm injection) cycles according to sperm origin.

Intracytoplasmic sperm injection increases embryo fragmentation without affecting clinical outcome.

The effects of sperm quality on embryo development after intracytoplasmic sperm injection.

Spermatogenic patterns and early embryo development after intracytoplasmic sperm injection in severe oligoasthenozoospermia.

Clinical experiences of ICSI-ET thawing cycles with embryos cryopreserved at different developmental stages.

Abdominal ultrasound-guided embryo transfer improves clinical pregnancy rates after in vitro fertilization: experiences from 330 clinical investigations.

Effect of ICSI on Subsequent Blastocyst Development and Pregnancy Rates

Administration of beta2-adrenergic agonists during the peri-implantation period does not improve implantation or pregnancy rates in intracytoplasmic sperm injection (ICSI) cycles.

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Administration of β 2-Adrenergic Agonists During the Peri-Implantation Period Does Not Improve Implantation or Pregnancy Rates in Intracytoplasmic Sperm Injection (ICSI) Cycles

Low-dose aspirin does not increase implantation rates in patients undergoing intracytoplasmic sperm injection: a prospective randomized study.

Pronuclear and morphological features as a cumulative score to select embryos in ICSI (intracytoplasmic sperm injection) cycles according to sperm origin.

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Administration of beta2-adrenergic agonists during the peri-implantation period does not improve implantation or pregnancy rates in intracytoplasmic sperm injection (ICSI) cycles.