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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Park, Yong-Seog Kim, Myo Kyung Lim, Chun Kyu Lee, Sun-Hee Park, Dong-Wook Seo, Ju Tae Yang, Kwang Moon |
| Description | Author Affiliation: Park YS ( Laboratory of Reproductive Medicine, Department of Urology, Department of Obstetrics and Gynecology, Cheil General Hospital & Women's Healthcare Center, Kwandong University College of Medicine, Seoul, 100-380, Republic of Korea, arkangel@daum.net.) |
| Abstract | PURPOSE: To evaluate the viability of frozen embryos generated by intracytoplasmic sperm injection (ICSI) with frozen testicular spermatozoa. METHODS: A total of 68 fresh embryo transfer (ET) cycles and 85 subsequent frozen-thawed ET (FET) cycles were grouped according to the source of spermatozoa: fresh testicular spermatozoa (TESE) or frozen-thawed testicular spermatozoa (t-TESE). RESULTS: There were no significant differences in the age of female patients, number of oocytes, or fertilization rates in fresh ET cycles with TESE (TESE-fresh ET) versus t-TESE (t-TESE-fresh ET). The rate of embryo survival after thawing (95.7 % vs. 94.0 %) was similar in frozen ET cycles (FET) with TESE (TESE-FET) and with t-TESE (t-TESE-FET). While there were significant differences in the proportion of good quality embryos, no statistical differences were found in the pregnancy or clinical abortion rates between the two groups. Moreover, delivery rates were not significantly different. CONCLUSIONS: Although the proportion of good quality embryos was affected by cryopreservation of testicular tissue, embryo survival rate was not. As well, subsequent pregnancy could be achieved successfully via t-TESE-FET cycles. Therefore, FET is not affected by the cryopreservation of testicular tissue, and avoids further oocyte retrieval and TESE procedures. |
| File Format | HTM / HTML |
| ISSN | 10580468 |
| e-ISSN | 15737330 |
| DOI | 10.1007/s10815-014-0304-2 |
| Journal | Journal of Assisted Reproduction and Genetics |
| Issue Number | 10 |
| Volume Number | 31 |
| Language | English |
| Publisher | Springer |
| Publisher Date | 2014-10-01 |
| Publisher Place | Netherlands |
| Access Restriction | Open |
| Subject Keyword | Discipline Reproductive Medicine Discipline Genectics Embryo Implantation Physiology Spermatozoa Testis Cryopreservation Embryo Transfer Fertilization In Vitro Freezing Oocyte Retrieval Oocytes Pregnancy Pregnancy Outcome Semen Preservation Sperm Injections, Intracytoplasmic |
| Content Type | Text |
| Resource Type | Article |
| Subject | Genetics Developmental Biology Reproductive Medicine Genetics (clinical) Obstetrics and Gynecology |
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