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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Rubinstein, Ethan Corey, G. Ralph Stryjewski, Martin E. Kanafani, Zeina A. |
| Description | Country affiliation: Canada Author Affiliation: Rubinstein E ( University of Manitoba, Faculty of Medicine, Section of Infectious Diseases, 543 - 745 Basic Medical Sciences Building, Winnipeg MB R3E 0J9, Canada. rubinste@cc.umanitoba.ca) |
| Abstract | INTRODUCTION: Hospital-acquired pneumonia is a common infection, associated with substantial mortality. Despite the increasing prevalence of nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus (MRSA), approved treatment options for this pathogen are limited. AREAS COVERED: This article reviews the pharmacokinetics, dosing, preclinical studies and clinical efficacy, and safety of telavancin, with a particular focus on results from trials in nosocomial pneumonia. PubMed and Congress websites were searched for relevant articles published between 2003 and 2010. EXPERT OPINION: Telavancin is a lipoglycopeptide antibiotic with rapid, bactericidal activity against MRSA, and may provide another option for the treatment of nosocomial pneumonia, owing to Gram-positive pathogens. |
| File Format | HTM / HTML |
| ISSN | 14656566 |
| Issue Number | 17 |
| Volume Number | 12 |
| e-ISSN | 17447666 |
| Journal | Expert Opinion on Pharmacotherapy |
| Language | English |
| Publisher | Taylor & Francis |
| Publisher Date | 2011-12-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Pharmacology Aminoglycosides Therapeutic Use Anti-bacterial Agents Cross Infection Drug Therapy Methicillin-resistant Staphylococcus Aureus Pneumonia, Staphylococcal Pharmacology Animals Gram-positive Bacterial Infections Humans Skin Diseases, Bacterial Journal Article Review |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pharmacology Pharmacology (medical) |
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