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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Ghanei, Mostafa Hosseini, Ali Reza Arabbaferani, Zohre Shahkarami, Efat |
| Description | Country affiliation: Iran Author Affiliation: Ghanei M ( Baqiyatallah Medical Sciences University, Research Center of Chemical Injuries, P.O. Box 19945-546, Mollasadra Street, Tehran, Iran.) |
| Abstract | BACKGROUND: : Coughing is one of the chronic respiratory symptoms of patients exposed to sulfur mustard (SM) used against Iranian combatants and civilians by Iraq during the Iran-Iraq war, between 1983 and 1989. This study carried out on SM exposed patients who referred to our clinic because of exacerbation of chronic cough. METHOD: : Fifty male SM injured patient in the age range of 21-79 years, all of them having chronic bronchitis and were suffering from chronic cough (>3 weeks) were evaluated. After history taking and performing physical examination our diagnostic evaluation included chest X-ray, pulmonary function test (PFT), para nasal computerized tomography, esophageal endoscopy and fiber optic bronchoscopy. RESULTS: : Apart from having chronic bronchitis as a constant disease in all patients, the other main causative factors behind chronic cough were bronchospasm, post-nasal drip syndrome (PNDS), and gastro esophageal reflux disease (GERD), which accounted for 66%, 46% and 44% of chronic cough of the patients, respectively. A single cause for chronic cough was found in 4 patients (8%), 2 causes in 17 patients (34%), 3 causes in 23 patients (46%) and 4 causes in 6 patients (12%). CONCLUSION: : Since a high majority of the patients had more than a single cause for chronic cough, multiplicity of causes of chronic cough in a patient is indicative for evaluation of possible exposure to chemical fumes, especially SM. Because of high prevalence of chronic bronchitis (100%) and bronchospasm (66%) among our study group we conclude that they should be considered at first, before assessment of other causes. |
| File Format | HTM / HTML |
| ISSN | 13826689 |
| Issue Number | 1 |
| Journal | Environmental Toxicology and Pharmacology |
| Volume Number | 20 |
| e-ISSN | 18727077 |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2005-07-01 |
| Publisher Place | Netherlands |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Environmental Health Discipline Pharmacology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Health, Toxicology and Mutagenesis Medicine Toxicology Pharmacology |
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