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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | McAdam-Marx, Carrie Bouchard, Jonathan Aagren, Mark Conner, Chris Brixner, Diana I. |
| Description | Country affiliation: United States Author Affiliation: McAdam-Marx C ( Department of Pharmacotherapy, University of Utah, Salt Lake City, Utah, USA. carrie.mcadammarx@pharm.utah.edu) |
| Abstract | OBJECTIVE: This cross-sectional study describes glycemic, body mass, and blood pressure (BP) control in patients with type 2 diabetes mellitus (T2DM) in an ambulatory care-based database of electronic medical records (EMRs). METHODS: Patients aged ≥18 years with T2DM documented in 2008 and with glycosylated hemoglobin (HbA(1c)) value, body mass index (BMI), and BP charted within 90 days before or after T2DM documentation were identified using the General Electric Centricity EMR research database. Control of glycemia (controlled, <7.0%; uncontrolled, ≥7.0% [intermediate, 7.0%- <9.0%; poor, ≥9.0%]), body mass (nonobese, <30 kg/ m(2); obese, ≥30 kg/m(2) [intermediate, 30-<35 kg/m(2); poor, ≥35 kg/m(2)]), and BP (controlled, <130/<80 mm Hg; uncontrolled, ≥130/≥80 mm Hg [intermediate, 130-<160/80-<100 mm Hg; poor, ≥160/≥100 mm Hg]) was identified, and patients were stratified by level of control individually and in combination. Comorbidities and antidiabetic and antihypertensive treatments prescribed in the year before the index date were identified in the EMR. RESULTS: The mean (SD) age of the cohort (N = 49,560) was 60.9 (12.4) years; 51.5% were female. A minority had controlled glycemia (36.4%), body mass (30.2%), and/or BP (36.4%). Of those with controlled glycemia and body mass, 44.8% also had controlled BP, representing 5.5% of the overall study population. CONCLUSIONS: Despite the potential selection bias, a minority of patients in this cross-sectional study were at HbA(1c), BP, or BMI goals, and even fewer gained control of all 3 of these risk factors. More intensive T2DM treatment with complementary efforts to manage body mass and BP is warranted in this population. |
| File Format | HTM / HTML |
| ISSN | 01492918 |
| Issue Number | 1 |
| Volume Number | 33 |
| e-ISSN | 1879114X |
| Journal | Clinical Therapeutics |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2011-01-01 |
| Publisher Place | United States |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Pharmacology Blood Glucose Drug Effects Blood Pressure Diabetes Mellitus, Type 2 Drug Therapy Adult Aged Ambulatory Care Antihypertensive Agents Therapeutic Use Body Mass Index Cross-sectional Studies Databases, Factual Complications Electronic Health Records Female Hemoglobin A, Glycosylated Metabolism Humans Hypoglycemic Agents Male Middle Aged Risk Factors Selection Bias Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pharmacology Pharmacology (medical) |
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