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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Hindy, Nicholas C. Solomon, Sarah H. Altmann, Gerry T. M. Thompson-Schill, Sharon L. |
| Description | Country affiliation: United States Author Affiliation: Hindy NC ( Department of Psychology, University of Pennsylvania, Philadelphia, PA 19104, USA Princeton Neuroscience Institute, Princeton University, Princeton, NJ 08540, USA.); Solomon SH ( Department of Psychology, University of Pennsylvania, Philadelphia, PA 19104, USA.); Altmann GT ( Department of Psychology, University of York, Heslington, York YO10 5DD, UK.); Thompson-Schill SL ( Department of Psychology, University of Pennsylvania, Philadelphia, PA 19104, USA.) |
| Abstract | Understanding events often requires recognizing unique stimuli as alternative, mutually exclusive states of the same persisting object. Using fMRI, we examined the neural mechanisms underlying the representation of object states and object-state changes. We found that subjective ratings of visual dissimilarity between a depicted object and an unseen alternative state of that object predicted the corresponding multivoxel pattern dissimilarity in early visual cortex during an imagery task, while late visual cortex patterns tracked dissimilarity among distinct objects. Early visual cortex pattern dissimilarity for object states in turn predicted the level of activation in an area of left posterior ventrolateral prefrontal cortex (pVLPFC) most responsive to conflict in a separate Stroop color-word interference task, and an area of left ventral posterior parietal cortex (vPPC) implicated in the relational binding of semantic features. We suggest that when visualizing object states, representational content instantiated across early and late visual cortex is modulated by processes in left pVLPFC and left vPPC that support selection and binding, and ultimately event comprehension. |
| File Format | HTM / HTML |
| ISSN | 10473211 |
| e-ISSN | 14602199 |
| DOI | 10.1093/cercor/bht275 |
| Journal | Cerebral Cortex |
| Issue Number | 4 |
| Volume Number | 25 |
| Language | English |
| Publisher | Oxford University Press |
| Publisher Date | 2015-04-01 |
| Publisher Place | United States |
| Access Restriction | Open |
| Subject Keyword | Discipline Neuroscience Discipline Neurology Cerebral Cortex Physiology Visual Perception Brain Mapping Imagination Magnetic Resonance Imaging Neural Pathways Neuropsychological Tests Research Support, N.i.h., Extramural Research Support, Non-u.s. Gov't Research Support, U.s. Gov't, Non-p.h.s. |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cognitive Neuroscience Cellular and Molecular Neuroscience |
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