| Content Provider |
World Health Organization (WHO)-Global Index Medicus |
| Author |
Kreißl, Sylvia Radon, Katja Dressel, Holger Genuneit, Jon Kellberger, Jessica Nowak, Dennis Von Mutius, Erika Weiland, Stephan K. Weinmayr, Gudrun Windstetter, Doris Vogelberg, Christian |
| Spatial Coverage |
Germany |
| Description |
Country affiliation: Germany Author Affiliation: Kreißl S ( Department of Pediatrics, University Hospital Carl Gustav Carus Dresden, Technische Universität Dresden, Dresden, Germany.); Radon K ( Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital Munich, Munich, Germany.); Dressel H ( Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital Munich, Munich, Germany.); Genuneit J ( Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany.); Kellberger J ( Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital Munich, Munich, Germany.); Nowak D ( Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital Munich, Munich, Germany.); von Mutius E ( Dr von Haunersches Children's Hospital, Ludwig Maximilians University, Munich, Germany.); Weiland SK ( Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany.); Weinmayr G ( Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany.); Windstetter D ( Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University Hospital Munich, Munich, Germany.); Vogelberg C ( Department of Pediatrics, University Hospital Carl Gustav Carus Dresden, Technische Universität Dresden, Dresden, Germany. Electronic address: christian.vogelberg@uniklinikum-dresden.de.) |
| Abstract |
BACKGROUND: Several studies have suggested an association between the increasing prevalence of allergic diseases and dietary factors. OBJECTIVE: To prospectively explore the association between changes in body mass index (BMI) and symptoms of asthma, rhinitis, rhinoconjunctivitis, and atopic dermatitis to find out whether an increase in BMI increases the risk of developing atopic diseases in adolescence. METHODS: Comprehensive questionnaires and anthropometric measurements were applied in a random subsample of the International Study of Asthma and Allergies in Childhood phase II (1995-1996, 9 to 11 years of age) in Germany. Of these participants, 1,794 could be followed up in 2002 to 2003 in the Study on Occupational Allergy Risks (16 to 18 years of age). The associations between changes of BMI from baseline to follow-up and incident and persistent respiratory diseases and atopic dermatitis were assessed. RESULTS: In logistic regression analyses, weight change in either direction was not statistically significantly associated with the incidence or persistence of any of the diseases of interest except for rhinitis. An increase in BMI was linked to an increased risk of incident rhinitis (odds ratio 1.9, 95% confidence interval 1.2-2.9). CONCLUSION: These results indicate a nonsignificant trend between increased body weight and risk of atopic diseases. Aside from limitations owing to a small subgroup of obese participants and questionnaire-based asthma diagnosis, reasons might be related to an interaction between BMI and hormonal influences, age, and duration and severity of overweight. The results underline that BMI does not necessarily play a decisive role in the course of atopic diseases in all populations. |
| File Format |
HTM / HTML |
| ISSN |
10811206 |
| Issue Number |
4 |
| Volume Number |
113 |
| e-ISSN |
15344436 |
| Journal |
Annals of Allergy, Asthma & Immunology |
| Language |
English |
| Publisher |
Elsevier (on behalf of the American College of Allergy, Asthma and Immunology) |
| Publisher Date |
2014-10-01 |
| Publisher Place |
United States |
| Access Restriction |
One Nation One Subscription (ONOS) |
| Subject Keyword |
Discipline Immunology Body Mass Index Body Weight Hypersensitivity, Immediate Epidemiology Obesity Adolescent Asthma Child Conjunctivitis, Allergic Dermatitis, Atopic Eczema Germany Humans Prospective Studies Rhinitis, Allergic, Perennial Rhinitis, Allergic, Seasonal Risk Factors Questionnaires Journal Article Research Support, Non-u.s. Gov't |
| Content Type |
Text |
| Resource Type |
Article |
| Subject |
Pulmonary and Respiratory Medicine Immunology and Allergy Immunology |
